Glucose homeostasis and weight loss in morbidly obese patients undergoing banded sleeve gastrectomy: a prospective clinical study

Glucose homeostasis and weight loss in morbidly obese patients undergoing banded sleeve gastrectomy: a prospective clinical study

Autor Miguel, Gustavo Peixoto Soares Autor UNIFESP Google Scholar
Azevedo, João Luiz Moreira Coutinho Autor UNIFESP Google Scholar
Gicovate Neto, Carlos Google Scholar
Moreira, Cora Lavigne Castelo Branco Google Scholar
Viana, Elaine Cristina Google Scholar
Carvalho, Perseu Seixas Google Scholar
Instituição Federal University of Espírito Santo
Universidade Federal de São Paulo (UNIFESP)
Resumo OBJECTIVE: To assess glucose homeostasis and weight loss in morbidly obese patients undergoing Silastic® ring sleeve gastrectomy. METHODS: This was a prospective clinical study. Thirty-three female patients with a mean body mass index (BMI) of 42.33 ± 1.50 kg/m² (range: 40-45 kg/m²), a mean age of 36.7 ± 9.4 years and a mean waist circumference of 118.7 ± 5.98 cm were included in this study. Type 2 diabetes mellitus was observed in 11 patients (33.3%), and glucose intolerance was observed in 4 patients (12.1%). Mean plasma fasting glucose levels were 109.77 ± 44.19 mg/dl (75-320) in the preoperative period. All Silastic® ring sleeve gastrectomy procedures were performed by the same surgical team using the same anesthetic technique. The patients were monitored for at least 12 months after surgery. RESULTS: The mean weight of the patients decreased from 107.69 ± 6.57 kg to 70.52 ± 9.36 kg (p < 0.001), the mean BMI decreased to 27.4 ± 2.42 kg/m² (p < 0.001), and the mean waist circumference decreased to 89.87 cm ± 6.66 (p < 0.001) in the postoperative period. Excess BMI loss was 86.5 ± 14.2%. Fasting glucose levels were reduced to 80.94 ± 6.3 mg/dl (p < 0.001). Remission of diabetes and glucose intolerance was observed in all patients. CONCLUSION: Silastic® ring sleeve gastrectomy was effective in promoting weight loss, waist circumference reduction and control of glucose homeostasis in morbidly obese patients.
Palavra-chave Type 2 diabetes mellitus
Obesity
Bariatric Surgery
Weight loss
Idioma Inglês
Data de publicação 2009-11-01
Publicado em Clinics. Faculdade de Medicina / USP, v. 64, n. 11, p. 1093-1098, 2009.
ISSN 1807-5932 (Sherpa/Romeo, fator de impacto)
Publicador Faculdade de Medicina / USP
Extensão 1093-1098
Fonte http://dx.doi.org/10.1590/S1807-59322009001100009
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000272487700008
SciELO S1807-59322009001100009 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/5323

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