Optical coherence tomography angiography artifacts in retinal pigment epithelial detachment

Optical coherence tomography angiography artifacts in retinal pigment epithelial detachment

Author Louzada, Ricardo N. Google Scholar
de Carlo, Talisa E. Google Scholar
Adhi, Mehreen Google Scholar
Novais, Eduardo A. Autor UNIFESP Google Scholar
Durbin, Mary K. Google Scholar
Cole, Emily Google Scholar
Lane, Mark Google Scholar
Moghimi, Omid Google Scholar
Arya, Malvika Google Scholar
Bonini Filho, Marco Google Scholar
Witkin, Andre J. Google Scholar
Baumal, Caroline R. Google Scholar
Avila, Marcos Google Scholar
Duker, Jay S. Google Scholar
Waheed, Nadia K. Google Scholar
Abstract Objective: To describe optical coherence tomography angiography (OCTA) reflectance artifacts secondary to retinal pigment epithelial detachment (RPED). Design: Retrospective review. Methods: Four eyes from 4 subjects were included. Three presented with RPED and 1 eye was a normal control. Two eyes diagnosed with RPED and the normal eye were evaluated using en face OCTA centred at the fovea acquired using the RTVue XR Avanti (Optovue Inc). In the third eye with RPED, OCTA imaging was performed using a CIRRUS 5000 prototype modified to do OCTA imaging on a spectral domain OCT platform provided by Carl Zeiss Meditec, Inc. The segmented OCTA angiograms were overlaid to determine if the flow patterns seen at the edge of the RPEDs were due to reflectance from the inner retinal vessels, also known as "decorrelation tails?' Results: OCTA projection artifacts were noted when segmentation lines intersected with the boundary of the RPED. The overlaid segmented OCTA from the 3 RPED eyes imaged using each system revealed the same vasculature pattern at the edges of the RPED as that of the inner retina, demonstrating the "decorrelation tails" artifact, which caused the RPED to appear as a bright ring on the segmented OCTA. Conclusions: OCTA images are susceptible to various known artifacts. This series describes the impact of the projection artifact seen at the edges of an RPED that simulates appearance of flow but is actually due to reflectance of the inner retinal vasculature on the RPED.
Language English
Sponsor Carl Zeiss Meditec
Topcon Medical Systems Inc.
Massachusetts Lions Clubs
Macula Vision Research Foundation, New York
CAPES Foundation, Ministry of Education of Brazil, Brasilia, DF, Brazil
Date 2017
Published in Canadian Journal Of Ophthalmology-Journal Canadien D Ophtalmologie. Ottawa, v. 52, n. 4, p. 419-424, 2017.
ISSN 0008-4182 (Sherpa/Romeo, impact factor)
Publisher Canadian Ophthal Soc
Extent 419-424
Origin http://dx.doi.org/10.1016/j.jcjo.2016.12.012
Access rights Closed access
Type Article
Web of Science ID WOS:000408431100033
URI http://repositorio.unifesp.br/handle/11600/51440

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