Use of fibrinogen and thrombin sponge in pediatric split liver transplantation

Use of fibrinogen and thrombin sponge in pediatric split liver transplantation

Author Piza Vicentine, Fernando Pompeu Autor UNIFESP Google Scholar
Gonzalez, Adriano Miziara Autor UNIFESP Google Scholar
Beninni, Barbara Burza Autor UNIFESP Google Scholar
de Azevedo, Ramiro Anthero Autor UNIFESP Google Scholar
Linhares, Marcelo Moura Autor UNIFESP Google Scholar
Goldenberg, Alberto Autor UNIFESP Google Scholar
Lopes Filho, Gaspar de Jesus Autor UNIFESP Google Scholar
Martins, Jose Luiz Autor UNIFESP Google Scholar
Salzedas Netto, Alcides Augusto Autor UNIFESP Google Scholar
Abstract Purpose: To analyze the use of this sponge in pediatric patients undergoing split-liver transplantation. Methods: Retrospective study, including 35 pediatric patients undergoing split-liver transplantation, divided into two groups according to the use of the sponge: 18 patients in Group A (no sponge) and 17 in Group B (with sponge). Results: The characteristics of recipients and donors were similar. We observed greater number of reoperation due to bleeding in the wound area in Group A (10 patients - 55.5%) than in Group B (3 patients - 17.6%)

p = 0.035. The median volume of red blood cells transfused in Group A was significantly higher (73.4 +/- 102.38 mL/kg) than that in Group B (35.1 +/- 41.67 mL/kg)

p = 0.048. Regarding bile leak there was no statistical difference. Conclusion: The use of the human fibrinogen and thrombin sponge, required lower volume of red blood cell transfusion and presented lower reoperation rates due to bleeding in the wound area.
Keywords Liver Transplantation
Homeostasis
Fibrinogen
Thrombin
Language English
Date 2017
Published in Acta Cirurgica Brasileira. Sao Paulo, v. 32, n. 8, p. 673-679, 2017.
ISSN 0102-8650 (Sherpa/Romeo, impact factor)
Publisher Acta Cirurgica Brasileira
Extent 673-679
Origin http://dx.doi.org/10.1590/s0102-865020170080000009
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000410613900009
SciELO ID S0102-86502017000800673 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/51425

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