Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil

Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil

Author Silvestre, Rodrigo Vellasco Duarte Google Scholar
Leal, Mariana Ferreira Autor UNIFESP Google Scholar
Demachki, Samia Google Scholar
Nahum, Márcia Cristina de Souza Google Scholar
Bernardes, Julio Guilherme Balieiro Google Scholar
Rabenhorst, Silvia Helena Barem Google Scholar
Smith, Marilia de Arruda Cardoso Autor UNIFESP Google Scholar
Mello, Wyller Alencar de Google Scholar
Guimarães, Adriana Costa Google Scholar
Burbano, Rommel Rodríguez Autor UNIFESP Google Scholar
Institution Departamento de Anatomia Patológica
Universidade Federal de São Paulo (UNIFESP)
Hospital Universitário João de Barros Barreto Departamento de Cirurgia
Universidade Federal do Ceará Escola de Medicina Departamento de Patologia e Medicina Forense
Ministério da Saúde Fundação Nacional de Saúde Fundação Nacional de Saúde
Universidade Federal do Pará Instituto de Ciências Biológicas Laboratório de Citogenética Humana
Abstract The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
Keywords human papillomavirus
prostate cancer
benign prostate hyperplasia
Language English
Date 2009-07-01
Published in Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 104, n. 4, p. 665-667, 2009.
ISSN 0074-0276 (Sherpa/Romeo, impact factor)
Publisher Instituto Oswaldo Cruz, Ministério da Saúde
Extent 665-667
Origin http://dx.doi.org/10.1590/S0074-02762009000400024
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000269466900024
SciELO ID S0074-02762009000400024 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/5133

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