Costs of hospitalization in preterm infants: impact of antenatal steroid therapy

Costs of hospitalization in preterm infants: impact of antenatal steroid therapy

Title: Costs of hospitalization in preterm infants: impact of antenatal steroid therapy;
Custos da hospitalização de recém-nascidos pré-termo: impacto da corticoterapia antenatal
Author Ogata, Joice Fabiola Meneguel [UNIFESP Google Scholar
Fonseca, Marcelo Cunio Machado Autor UNIFESP Google Scholar
Miyoshi, Milton Harumi Autor UNIFESP Google Scholar
Almeida, Maria Fernanda Branco de Autor UNIFESP Google Scholar
Guinsburg, Ruth Autor UNIFESP Google Scholar
Abstract Objective: To estimate the costs of hospitalization in premature infants exposed or not to antenatal corticosteroids (ACS). Method: Retrospective cohort analysis of premature infants with gestational age of 26-32 weeks without congenital malformations, born between January of 2006 and December of 2009 in a tertiary, public university hospital. Maternal and neonatal demographic data, neonatal morbidities, and hospital inpatient services during the hospitalization were collected. The costs were analyzed using the microcosting technique. Results: Of 220 patients that met the inclusion criteria, 211 (96%) charts were reviewed: 170 newborns received at least one dose of antenatal corticosteroid and 41 did not receive the antenatal medication. There was a 14-37% reduction of the different cost components in infants exposed to ACS when the entire population was analyzed, without statistical significance. Regarding premature infants who were discharged alive, there was a 24-47% reduction of the components of the hospital services costs for the ACS group, with a significant decrease in the length of stay in the neonatal intensive care unit (NICU). In very-low birth weight infants, considering only the survivors, ACS promoted a 30-50% reduction of all elements of the costs, with a 36% decrease in the total cost (p = 0.008). The survivors with gestational age < 30 weeks showed a decrease in the total cost of 38% (p = 0.008) and a 49% reduction of NICU length of stay (p = 0.011). Conclusion: ACS reduces the costs of hospitalization of premature infants who are discharged alive, especially those with very low birth weight and < 30 weeks of gestational age. (C) 2015 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.
Keywords Preterm Infant
Costs And Cost Analysis
Hospitalization
GlucocorticoidsRespiratory-Distress-Syndrome
Birth
Prevention
Mortality
Survival
Deaths
Risk
Language English
Date 2016
Published in Jornal De Pediatria. Rio de janeiro, rj, v. 92, n. 1, p. 24-31, 2016.
ISSN 0021-7557 (Sherpa/Romeo, impact factor)
Publisher Soc brasil pediatria
Extent 24-31
Origin http://dx.doi.org/10.1016/j.jped.2015.03.004
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000371471300005
SciELO ID S0021-75572016000100024 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/49593

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