Can breast tumors affect the oxidative status of the surrounding environment? A comparative analysis among cancerous breast, mammary adjacent tissue, and plasma

Can breast tumors affect the oxidative status of the surrounding environment? A comparative analysis among cancerous breast, mammary adjacent tissue, and plasma

Author Panis, C. Google Scholar
Victorino, V. J. Google Scholar
Herrera, A. C. S. A. Google Scholar
Cecchini, A. L. Google Scholar
Simao, A. N. C. Google Scholar
Tomita, L. Y. Autor UNIFESP Google Scholar
Cecchini, R. Google Scholar
Abstract In this paper, we investigated the oxidative profile of breast tumors in comparison with their normal adjacent breast tissue. Our study indicates that breast tumors present enhanced oxidative/nitrosative stress, with concomitant augmented antioxidant capacity when compared to the adjacent normal breast. These data indicate that breast cancers may be responsible for the induction of a prooxidant environment in the mammary gland, in association with enhanced TNF-alpha and nitric oxide.
Keywords Nipple Aspirate Fluids
Lipid-Peroxidation
Stress
Microenvironment
Women
Proteins
Progression
Estrogen
Profile
Marker
Language English
Sponsor CAPES
CNPq
Fundacao Araucaria
Date 2016
Published in Oxidative Medicine And Cellular Longevity. London, 2016.
ISSN 1942-0900 (Sherpa/Romeo, impact factor)
Publisher Hindawi ltd
Origin http://dx.doi.org/10.1155/2016/6429812
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000372235600001
URI http://repositorio.unifesp.br/handle/11600/49582

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