Morphological and biochemical effects on the skeletal muscle of ovariectomized old female rats submitted to the intake of diets with vegetable or animal protein and resistance training

Morphological and biochemical effects on the skeletal muscle of ovariectomized old female rats submitted to the intake of diets with vegetable or animal protein and resistance training

Author Braggion, Glaucia Figueiredo Google Scholar
Ornelas, Elisabete Google Scholar
Sattin Cury, Jurema Carmona Google Scholar
Alves Lima, Natalia Edviges Google Scholar
Aquino, Rita C. Google Scholar
Affonso Fonseca, Fernando Luiz Autor UNIFESP Google Scholar
Mesiano Maifrino, Laura Beatriz Google Scholar
Abstract Introduction. Sarcopenia is a process characterized by reduction in protein mass and muscle strength with increasing age, especially in the postmenopausal period, resulting in functional limitations and with great impact on the physical autonomy of the elderly. Objective. To evaluate the effects of diets with vegetable proteins (VP) or animal proteins (AP) associated with resistance training (RT) on the structural and biochemical parameters of the medial gastrocnemius muscle in Wistar rats with sarcopenia. Methods. An experimental model with ovariectomized rats was used to induce sarcopenia and resistance training. The histochemical technique was used for the typing of muscle fibers, the cross-sectional area of myocytes, and volume densities of myocytes and interstitium

the technique of Picrosirius stain was used to highlight the collagen fibers. Results. The VP diet was not able to minimize the effects of sarcopenia in the medial gastrocnemius of sedentary animals and when associated with RT, it promoted maintenance of the CSA, attenuating the atrophy of type IIB fibers in the medial gastrocnemius. The AP diet in sedentary animals protected the type I fibers. When combined with RT, the AP promoted muscle remodeling, with reduction in volume density of type I and IIA fibers, and increase of IIB fibers, together with an increase in collagen volume density. Conclusion. The data suggest a tendency to better results of hypertrophy in animal groups that consumed the AP diet, even the sedentary animals, although more evident in those trained.
Keywords Contractile Properties
Insulin-Resistance
Anabolic Response
Physical Function
Norway Rats
Lean Mass
Sarcopenia
Strength
Exercise
Age
Language English
Date 2016
Published in Oxidative Medicine And Cellular Longevity. London, 2016.
ISSN 1942-0900 (Sherpa/Romeo, impact factor)
Publisher Hindawi ltd
Origin http://dx.doi.org/10.1155/2016/9251064
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000374070300001
URI http://repositorio.unifesp.br/handle/11600/49544

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