Peritoneal infection by Candida albicans: study of number and size of limphocytes and phagocitic activy of peritoneal machophages in mice

Peritoneal infection by Candida albicans: study of number and size of limphocytes and phagocitic activy of peritoneal machophages in mice

Autor Saad, Flávio Autor UNIFESP Google Scholar
Silva, Maria Regina R. da Autor UNIFESP Google Scholar
Hayashi, Hisakazu Autor UNIFESP Google Scholar
Gompertz, Olga Fischman Autor UNIFESP Google Scholar
Segreto, Roberto Araujo Autor UNIFESP Google Scholar
Segreto, Helena Regina Comodo Autor UNIFESP Google Scholar
Barbiéri, Clara Lúcia Autor UNIFESP Google Scholar
Novo, Neil Ferreira Autor UNIFESP Google Scholar
Juliano, Yara Autor UNIFESP Google Scholar
Plapler, Helio Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The main purpose of this investigation was to stdy some aspects of leucocytes (granulocytes and limphocytes) and the phagocitic activity of peritoneal macrophages. In this experimen, which took place at Escola Paulista de Medicina - Universidade Federal de São Paulo (UNIFESP) - Brazil, it was used twenty female C57BLACK mice. Half of them were submitted to radiation to obtain immunossupressed animals (Group A - irradiated mice). The other ten mice were not iiradiated (Group B - control). The animals were sorted in four subgroups A-2 and B-2, were infected with Candida albicans (ATCC 90029). The resultant data showed significant differences in the number of leucocytes (granulocytes and limphocytes), and in the medium size of limphocytes between irradiated and non irradiated mice. Related to peritoneal macrophages, it was observed that the number of macrophages was lower in irradiated mice and the phagocitic was decreased in the irradiated and infected animals.
Palavra-chave Peritonitis
Candida albicans
Ionizing radiation
Leucocytes
Macrophages
Idioma Inglês
Data de publicação 1997-06-01
Publicado em Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 12, n. 2, p. 100-103, 1997.
ISSN 0102-8650 (Sherpa/Romeo)
Publicador Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Extensão 100-103
Fonte http://dx.doi.org/10.1590/S0102-86501997000200005
Direito de acesso Acesso aberto Open Access
Tipo Artigo
SciELO S0102-86501997000200005 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/495

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