Development of silver nanoparticles-based sensor for detection of quinolones by surface-enhanced raman spectroscopy: a case-study using levofloxacin

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dc.contributor.author Madalossi, Natiara V.
dc.contributor.author Mazali, Italo O.
dc.contributor.author Corbi, Fabiana C. A.
dc.contributor.author Sigoli, Fernando A.
dc.contributor.author Santos, Elias B. [UNIFESP]
dc.date.accessioned 2019-01-21T10:29:47Z
dc.date.available 2019-01-21T10:29:47Z
dc.date.issued 2016
dc.identifier http://dx.ddoi.org/10.3303/CET1647006
dc.identifier.citation International Conference On Nanotechnology Based Innovative Applications For The Environment. Milano, v. 47, p. 31-36, 2016.
dc.identifier.issn 1974-9791
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/49395
dc.description.abstract Numerous studies have shown that a variety of pharmaceuticals such as quinolones have been detected in the vicinity of municipal wastewater discharges and livestock agricultural facilities. Many of those works have been employed conventional analytical techniques and traditional methods of detection. However, in many cases these detection methodologies are time consuming and generate waste, which can be overcome using Surface-enhanced Raman spectroscopy (SERS) as analytical technique. In the present work, silver nanoparticles (AgNP) films were prepared on amine-modified glass slides with different number of depositions. The AgNP aggregates films were tested as SERS substrates using 4-aminobenzenethiol (4-ABT) as model Raman molecule. A trend between the 4-ABT SERS response and the number of AgNP deposition could be identified, which can be associated with the formation of AgNP aggregates. The aggregation effect could be quantified by calculating the enhancement factor (EF), which was on order of 10(6) for the film with five AgNP depositions. This optimized AgNP film was employed as SERS sensor of Levofloxacin in different concentrations, which was easily detected from 10(-4), 10(-5), and 10(-6) mol L-1 solution. Also, the SERS spectral profile are rich in information, which allowed to describe the chemical interaction between the Levofloxacin molecules and the AgNP sensor surface. This study provides an efficient method for detecting of Levofloxacin using AgNP SERS sensor, which can be extended for others quinolones. en
dc.format.extent 31-36
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartof International Conference On Nanotechnology Based Innovative Applications For The Environment
dc.rights Acesso restrito
dc.subject Gold Nanoparticles en
dc.subject Scattering en
dc.subject 4-Aminobenzenethiol en
dc.subject Aggregation en
dc.title Development of silver nanoparticles-based sensor for detection of quinolones by surface-enhanced raman spectroscopy: a case-study using levofloxacin en
dc.type Trabalho apresentado em evento
dc.description.affiliation Functional Materials Laboratory, Institute of Chemistry – University of Campinas, Campinas - SP, Brazil
dc.description.affiliation Institute of Science and Technology-Federal University of São Paulo, São José do Campos - SP, Brazil
dc.description.affiliationUnifesp Institute of Science and Technology-Federal University of São Paulo, São José do Campos - SP, Brazil
dc.identifier.doi 10.3303/CET1647006
dc.description.source Web of Science
dc.identifier.wos WOS:000383875000006



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