Impact of psychiatric disorders on the quality of life of brazilian HCV-infected patients

Impact of psychiatric disorders on the quality of life of brazilian HCV-infected patients

Author Batista-Neves, Susana Google Scholar
Quarantini, Lucas de Castro Autor UNIFESP Google Scholar
Almeida, Amanda Cristina Galvão Oliveira de Autor UNIFESP Google Scholar
Cardeal, Maurício Google Scholar
Lacerda, Acioly Luiz Tavares de Autor UNIFESP Google Scholar
Paraná, Raymundo Google Scholar
Reis De-Oliveira, Irismar Google Scholar
Bressan, Rodrigo Affonseca Autor UNIFESP Google Scholar
Miranda-Scippa, Ângela Marisa de Aquino Autor UNIFESP Google Scholar
Institution Federal University of Bahia Hospital Universitário
Universidade Federal de São Paulo (UNIFESP)
Abstract The aim of our study was to determine the impact of psychiatric comorbidities on the health-related quality of life of HCV-infected patients. Assessment of clinical, socio-demographic and quality of life data of the patients followed up at a Hepatology unit was performed by using a standard questionnaire and the SF-36 instrument. Psychiatric diagnoses were confirmed by using the Mini International Neuropsychiatric Interview, Brazilian version 5.0.0 (MINI Plus). Evaluation using the MINI plus demonstrated that 46 (51%) patients did not have any psychiatric diagnosis, while 44 (49%) had at least one psychiatric diagnosis. Among patients with a psychiatric comorbidity, 26 (59.1%) had a current mental disorder, out of which 22 (84.6%) had not been previously diagnosed. Patients with psychiatric disorders had lower scores in all dimensions of the SF-36 when compared to those who had no psychiatric diagnosis. Scores of physical functioning and bodily pain domains were lower for those suffering from a current psychiatric disorder when compared to those who had had a psychiatric disorder in the past. Females had lower scores of bodily pain and mental health dimensions when compared to males. Scores for mental health dimension were also lower for patients with advanced fibrosis. The presence of a psychiatric comorbidity was the variable that was most associated with the different scores in the SF-36, compared to other variables such as age, gender, aminotransferase levels, and degree of fibrosis.
Keywords Mental disorders
quality of life
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Date 2009-02-01
Published in Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 13, n. 1, p. 40-43, 2009.
ISSN 1413-8670 (Sherpa/Romeo, impact factor)
Publisher Brazilian Society of Infectious Diseases
Extent 40-43
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000267703200009
SciELO ID S1413-86702009000100009 (statistics in SciELO)

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