Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus

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dc.contributor.author Nicolau, Sergio Mancini [UNIFESP]
dc.contributor.author Martins, Nelson Valente [UNIFESP]
dc.contributor.author Ferraz, Paulo Eduardo [UNIFESP]
dc.contributor.author Stávale, João Norberto [UNIFESP]
dc.contributor.author Goncalves, Wagner Jose [UNIFESP]
dc.contributor.author Baracat, Edmund Chada [UNIFESP]
dc.contributor.author Lima, Geraldo Rodrigues de [UNIFESP]
dc.date.accessioned 2015-06-14T13:24:34Z
dc.date.available 2015-06-14T13:24:34Z
dc.date.issued 1997-02-01
dc.identifier http://dx.doi.org/10.1590/S1516-31801997000100003
dc.identifier.citation São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997.
dc.identifier.issn 1516-3180
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/464
dc.description.abstract INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men. en
dc.description.abstract INTRODUÇÃO: A infecção genital masculina pelo papilomavírus humano tem especial importância, pois é, freqüentemente, assintomática. Na maioria dos casos, o indivíduo não apresenta lesão clínica. Por isso, os homens passam a ser encarados como importante reservatório do vírus, exercendo papel especial na transmissão e perpetuação da doença. PACIENTES E MÉTODOS: No presente estudo clínico do tipo prospectivo, foram avaliados 190 parceiros de mulheres com infecção genital por papilomavírus humano, associada ou não à neoplasia intra-epitelial cervical. Todos os pacientes desconheciam ou negavam a presença de lesão genital. RESULTADOS: A citologia uretral exibiu coilocitose em nove casos (4,7%) e três (1,6%) na coroa da glande e prepúcio distal. A peniscopia, após a aplicação de ácido acético a 5%, revelou lesões brancas em 97,9% dos pacientes. A solução do azul de toluidina corou a maior parte das lesões observadas, Pelo menos um fragmento revelou coilocitose quando do estudo histopatológico em 97 casos (51,05%). CONCLUSÃO: Os três métodos se complementam, permitindo diagnóstico mais preciso dessa infecção no homem. pt
dc.format.extent 1330-1335
dc.language.iso eng
dc.publisher Associação Paulista de Medicina - APM
dc.relation.ispartof São Paulo Medical Journal
dc.rights Acesso aberto
dc.subject Peniscopy en
dc.subject papillomavirus en
dc.subject HPV en
dc.subject colposcopy en
dc.title Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Escola Paulista de Medicina Department of Obstetrics and Gynecology
dc.description.affiliation Escola Paulista de Medicina Department of Pathological Anatomy
dc.description.affiliationUnifesp UNIFESP, EPM, Department of Obstetrics and Gynecology
dc.description.affiliationUnifesp Escola Paulista de Medicina Department of Pathological Anatomy
dc.identifier.file S1516-31801997000100003.pdf
dc.identifier.scielo S1516-31801997000100003
dc.identifier.doi 10.1590/S1516-31801997000100003
dc.description.source SciELO



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