Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus

Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus

Author Nicolau, Sergio Mancini Autor UNIFESP Google Scholar
Martins, Nelson Valente Autor UNIFESP Google Scholar
Ferraz, Paulo Eduardo Autor UNIFESP Google Scholar
Stávale, João Norberto Autor UNIFESP Google Scholar
Goncalves, Wagner Jose Autor UNIFESP Google Scholar
Baracat, Edmund Chada Autor UNIFESP Google Scholar
Lima, Geraldo Rodrigues de Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.

INTRODUÇÃO: A infecção genital masculina pelo papilomavírus humano tem especial importância, pois é, freqüentemente, assintomática. Na maioria dos casos, o indivíduo não apresenta lesão clínica. Por isso, os homens passam a ser encarados como importante reservatório do vírus, exercendo papel especial na transmissão e perpetuação da doença. PACIENTES E MÉTODOS: No presente estudo clínico do tipo prospectivo, foram avaliados 190 parceiros de mulheres com infecção genital por papilomavírus humano, associada ou não à neoplasia intra-epitelial cervical. Todos os pacientes desconheciam ou negavam a presença de lesão genital. RESULTADOS: A citologia uretral exibiu coilocitose em nove casos (4,7%) e três (1,6%) na coroa da glande e prepúcio distal. A peniscopia, após a aplicação de ácido acético a 5%, revelou lesões brancas em 97,9% dos pacientes. A solução do azul de toluidina corou a maior parte das lesões observadas, Pelo menos um fragmento revelou coilocitose quando do estudo histopatológico em 97 casos (51,05%). CONCLUSÃO: Os três métodos se complementam, permitindo diagnóstico mais preciso dessa infecção no homem.
Keywords Peniscopy
papillomavirus
HPV
colposcopy
Language English
Date 1997-02-01
Published in São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997.
ISSN 1516-3180 (Sherpa/Romeo)
Publisher Associação Paulista de Medicina - APM
Extent 1330-1335
Origin http://dx.doi.org/10.1590/S1516-31801997000100003
Access rights Open access Open Access
Type Article
SciELO ID S1516-31801997000100003 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/464

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