Enteral nutrition during bone marrow transplantation in patients with pediatric cancer: a prospective cohort study

Enteral nutrition during bone marrow transplantation in patients with pediatric cancer: a prospective cohort study

Author Garófolo, Adriana Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract CONTEXT AND OBJECTIVE: Cancer patients undergoing bone marrow transplantation (BMT) often require nutritional therapy due to treatment toxicities. The aim here was to evaluate the use of tube feeding and its applicability, indications, contraindications and complications in these patients.DESIGN AND SETTING: Prospective observational study conducted at a public university in Sao Paulo between January 2002 and August 2007.METHODS: The patients were followed up daily in the BMT unit by a research dietitian. Tube feeding was indicated when oral supplementation proved to be insufficient, when the patient had severe malnutrition or there was an impediment to use of oral feeding. It was contraindicated in the presence of gastrointestinal toxicity of grade 3 and 4 or other conditions that implied a risk or hindered its use or placement. Complications of tube feeding were divided into minor and major, according to whether they had life-threatening implications.RESULTS: Forty-two (47.2%) patients had indications for tube feeding: the main reasons were transplantation inadequate food and supplement intake, insufficient intake with malnutrition or weight loss, severe malnutrition or need for oral fasting. Thirty-one (73.8%) received tube feeding: 11 autologous and 20 allogenic patients (P = 0.04). The main contraindications were severe gastrointestinal toxicities and sinusitis. Minor complications from tube feeding were more prevalent in patients with allogenic BMT, but no major complications were observed.CONCLUSION: Enteral nutrition is a feasible procedure in patients undergoing BMT and should be encouraged. The main difficulty in BMT patients, in relation to tube feeding, is gastrointestinal toxicities.
Keywords Transplants
Enteral nutrition
Language English
Date 2012-01-01
Published in Sao Paulo Medical Journal. Sao Paulo: Associacao Paulista Medicina, v. 130, n. 3, p. 159-166, 2012.
ISSN 1516-3180 (Sherpa/Romeo, impact factor)
Publisher Associacao Paulista Medicina
Extent 159-166
Origin http://dx.doi.org/10.1590/S1516-31802012000300005
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000306368400005
SciELO ID S1516-31802012000300005 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/45557

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