Intestinal metaplasia in gallbladders: prevalence study

Intestinal metaplasia in gallbladders: prevalence study

Alternative title Metaplasia intestinal na vesícula biliar: estudo da prevalência
Author Fernandes, Jose Eduardo Vasconcelos Google Scholar
Franco, Maria Isete Fares Google Scholar
Suzuki, Reinaldo Kenji Google Scholar
Tavares, Nelson Mattos Google Scholar
Bromberg, Sansom Henrique Autor UNIFESP Google Scholar
Institution Hosp Serv Publ Estadual Sao Paulo
Univ Metropolitana Santos
Universidade de São Paulo (USP)
Univ Lusiada
Santa Casa Misericordia Santos
Universidade Federal de São Paulo (UNIFESP)
Abstract CONTEXT AND OBJECTIVE: Gallbladder cancer is usually diagnosed at a late stage and generally results in death. Discovery of predisposing factors for this neoplasia could prevent this outcome. In this study, we assess the presence of one of these factors: intestinal metaplasia in gallbladders with stones and inflammatory processes.DESIGN AND SETTING: Cross-sectional study in Hospital do Servidor Publico Estadual de Sao Paulo.METHOD: The first 80 gallbladders from patients who underwent elective cholecystectomy between April and August 2002, presenting stones and chronic inflammation, were studied. The patients were divided into groups according to their age: CC 1, from 15 to 40 years; CC2, from A I to 60 years; and CC3, from 61 to 85 years.RESULTS: Twenty-one patients (26%) were male, while 59 (74%) were female. In the group CC 1, intestinal metaplasia was present in 85.71% of the 21 patients studied; in CC2, in 79.41% of 34 patients; and in CC3, in 56.00% of 25 patients. These differences presented statistical significance (p = 0.04542).CONCLUSION: Intestinal metaplasia is extremely frequent in gallbladders with inflammation and lithiasis, especially in younger patients.
Keywords Lithiasis
Cholecystitis
Gallbladder
Metaplasia
Cholecystectomy
Language English
Date 2008-07-03
Published in Sao Paulo Medical Journal. Sao Paulo: Associacao Paulista Medicina, v. 126, n. 4, p. 220-222, 2008.
ISSN 1516-3180 (Sherpa/Romeo, impact factor)
Publisher Associacao Paulista Medicina
Extent 220-222
Origin http://dx.doi.org/10.1590/S1516-31802008000400004
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000260203000004
SciELO ID S1516-31802008000400004 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/45542

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