Glucose absorption by the interposed colon segment after extensive intestinal resection

Glucose absorption by the interposed colon segment after extensive intestinal resection

Author Plapler, Helio Autor UNIFESP Google Scholar
Fagundes, Djalma José Autor UNIFESP Google Scholar
Goldenberg, Saul Autor UNIFESP Google Scholar
Novo, Neil Ferreira Autor UNIFESP Google Scholar
Juliano, Yara Autor UNIFESP Google Scholar
Bekhor, Daniel Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract One of the proposed surgical treatments of Short Bowel Syndrome is the interposition of a distal colon segment between two portions of the remnant small intestine. This method proved to reverse the nutritional disorders caused by this morbid entity. Surgical technique consisted in an 80 % small bowel resection and the interposition of a 3 cm segment of distal colon between the remaining jejunum and ileum. After 70 days, the animals were reoperated and the interposed and the distal colon were isolated and tied. By using the method of rapid and successive absorptions of a glucose solution through the intestinal lumen, the relations between the absorption curves of the interposed and the normal colon could be dran. Results show that the interposed colon segment absorbs more glucose (mean = 1.43 +/- 1.16 mg/dl) than the distal colon (mean = 0.37 +/- 0.29 mg/dl) and that its absorption pattern is similar to the small bowel rather than the colon. These results allow the use of this method for further studies in which the interposed colon adaptation is studied with other nutrients and/or under specific conditions.
Language English
Date 1992-09-01
Published in Revista Espanola De Fisiologia. Pamplona: Rev Espanola Fisiologia, v. 48, n. 3, p. 197-201, 1992.
ISSN 0034-9402 (Sherpa/Romeo, impact factor)
Publisher Rev Espanola Fisiologia
Extent 197-201
Access rights Closed access
Type Article
Web of Science ID WOS:A1992KP57300009

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