Transtorno afetivo bipolar: carga da doença e custos relacionados

Transtorno afetivo bipolar: carga da doença e custos relacionados

Alternative title Bipolar disorder: burden of disease and related costs
Author Niccolai Costa, Anna Maria Google Scholar
Institution Bristol Myers Squibb Co
Universidade Federal de São Paulo (UNIFESP)
Abstract Background: Bipolar disorder (BD) is a recurrent, chronic and severe disease. Mental and physical comorbidities, risk of suicide, health services use and impairment of social and professional domains significantly worsen the burden and increase the costs of illness. Objectives: Review clinical aspects, burden of disease, and consequent financial outcomes of BD. Methods: MEDLINE/PubMed database search using the terms bipolar disorder, epidemiology, burden of disease, comorbidity, cost of illness, outcomes e financial consequences, published in MEDLINE from 1980 to 2006. Results: BD has a high rate of comorbidities, which worsen the prognosis and increase costs with health services. Subjects with BD have more cardiovascular risk factors than the general population, and therefore a higher risk of death by cardiovascular event. Delay of diagnosis and misdiagnosis increase the costs of illness. Discussion: Comorbidities, risk of suicide, social and professional impairment and low adherence to treatment increase the cost of illness. The search of comorbidities may help clinicians to adjust treatment strategies, taking into account all associated risk factors and costs, which may be considered also by professionals involved in health care management, either private or public.
Keywords psychiatry
bipolar disorder
cost of illness
mental health
Language Portuguese
Date 2008-01-01
Published in Revista De Psiquiatria Clinica. Sao Paulo: Univ Sao Paulo, Inst Psiquiatria, v. 35, n. 3, p. 104-110, 2008.
ISSN 0101-6083 (Sherpa/Romeo, impact factor)
Publisher Univ Sao Paulo, Inst Psiquiatria
Extent 104-110
Access rights Open access Open Access
Type Review
Web of Science ID WOS:000257955200003
SciELO ID S0101-60832008000300003 (statistics in SciELO)

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