The Portuguese version of the clinical global impression - Schizophrenia scale: validation study

The Portuguese version of the clinical global impression - Schizophrenia scale: validation study

Alternative title Versão em português da Impressão Clínica Global - Escala de Esquizofrenia: estudo de validação
Author Lima, Mauricio Silva de Autor UNIFESP Google Scholar
Soares, Bernardo Garcia de Oliveira Autor UNIFESP Google Scholar
Paoliello, Gilda Google Scholar
Vieira, Rodrigo Machado Google Scholar
Martins, Claudio Meneghello Google Scholar
Mota Neto, Joaquim Ignacio da Google Scholar
Ferrão, Ygor Arzeno Google Scholar
Schirmer, Douglas Allen Google Scholar
Volpe, Fernando Madalena Autor UNIFESP Google Scholar
Institution Univ Fed Pelotas
Eli Lilly & Co
Universidade Federal de São Paulo (UNIFESP)
Hosp Espirita Porto Alegre
Abstract Objectives: The Clinical Global Impression - Schizophrenia Scale was designed to assess severity and treatment response in subjects with schizophrenia involved in naturalistic studies and daily clinical practice. The objective of this study is to validate the Portuguese version of the Clinical Global Impression - Schizophrenia Scale in Brazil by assessing its psychometric properties. Method: Cross-sectional validation study of the Portuguese version of the Clinical Global Impression - Schizophrenia Scale, tested in outpatients and inpatients with schizophrenia (DSM-IV, ICD-10) from 6 centers in Brazil. Concurrent validity and sensitivity to change were assessed by comparison with the Positive and Negative Syndrome Scale, which is considered the gold standard tool to evaluate patients with schizophrenia. Interrater reliability was evaluated by intraclass correlation coefficients (ICC) calculated based on the scoring of two concomitant raters. Results: 70 inpatients and 70 outpatients were evaluated. Total Clinical Global Impression - Schizophrenia Scale and Positive and Negative Syndrome Scale scores were highly correlated (r = 0.79; p < 0.01). Positive (r = 0.86), negative (r = 0.79), depressive (r = 0.66) and cognitive (r = 0.75) symptoms subscale scores were also correlated between both scales (P < 0.01). Sensitivity to change was significantly correlated between the Clinical Global Impression - Schizophrenia Scale and Positive and Negative Syndrome Scale (r = 0.73; p < 0.01). Interrater reliability was substantial for positive symptoms and total scores of the Clinical Global Impression - Schizophrenia Scale (ICC = 0.81 and 0.73), and moderate for negative, depressive, and cognitive symptoms score (0.64, 0.67 and 0.63, respectively). Conclusions: The Brazilian version of the Clinical Global Impression - Schizophrenia Scale is a valid and reliable instrument for the assessment of severity and treatment response in schizophrenic inpatient and outpatients.
Keywords schizophrenia
psychiatric status rating scales
validity of tests
validation studies
multicenter study
Language English
Date 2007-09-01
Published in Revista Brasileira De Psiquiatria. Sao Paulo: Assoc Brasileira Psiquiatria, v. 29, n. 3, p. 246-249, 2007.
ISSN 1516-4446 (Sherpa/Romeo, impact factor)
Publisher Assoc Brasileira Psiquiatria
Extent 246-249
Origin http://dx.doi.org/10.1590/S1516-44462006005000047
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000249455200010
SciELO ID S1516-44462007000300010 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/45398

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