Estudo retrospectivo da utilização do transplante de membrana amniótica em um serviço terciário de Oftalmologia

Estudo retrospectivo da utilização do transplante de membrana amniótica em um serviço terciário de Oftalmologia

Título alternativo Retrospective study of amniotic membrane transplantation in a terciary ophthalmic health care service
Autor Oliveira, Eduardo Conforti de Google Scholar
Ramos, Gabriel Zatti Google Scholar
Afonso, Vivian Cristina Costa Google Scholar
Souza, Luciene Barbosa Autor UNIFESP Google Scholar
Instituição HOS
Universidade Federal de São Paulo (UNIFESP)
Resumo Objective: During the last years amniotic membrane (AM) autograft has been frequently used for reconstruction of the ocular surface in many diseases. This study intends to analyze the major indications for AM as well the results of this procedure. Methods: Data of 107 patients who had done AM autograft surgery were retrospectively analised regarding the indications and postoperatory follow-up. Results: The indications for AM autograft was ptherygium 33.64% (n=36), persistent epithelial defect 29.90% (n=32), simblepharum 18.69% (n=20), chemical injury 6.54%(n=7), vernal conjunctivitis 4.67% (n=5), Stevens-Johnson 2.80% (n=3), ocular cicatricial penfigoid 1.86% (n=2), bullous keratopathy 1.86%(n=2). At the follow-up of ptherygium was observed recurrence between 6,25%(in primary ptherygium) and 15% (in recurrence ptherygium). No recurrence was observed in simblepharum surgery for complications due ptherygium. Recovery of epithelial integrity was between 50 and 80% depending the disease. In the acute phase of chemical burns recovery was observed in 50%, however in chronic chemical burns the recovery was only in 33% of the cases. The AM in vernal conjunctivitis to resolve giant papillae, 80% of the cases showed good evolution. In 100% of the case due bullous keratopathy the patients had improvement of the pain. In Steven-Johnsons syndrome (SJS) at the acute phase the patients had improevment of the inflammatory component. In the chronic phase of SJS, 50% of the patients had favorable evolution after the procedure. Conclusion: Amniotic membrane autograft showed promising results for the majority ocular surface diseases enrroled in this study. This surgical tecnic cheap and easy doing asweel a good therapeutic alternative for many ocular surface diseases.
Assunto amnio/transplantation
reconstructive surgical procedures/trends
tissue transplantation
eye diseases/surgery
conjunctival diseases/surgery
corneal diseases/surgery
retrospective studies
Idioma Português
Data 2008-07-01
Publicado em Revista Brasileira De Oftalmologia. Rio De Janeiro: Soc Brasileira Oftalmologia, v. 67, n. 4, p. 165-171, 2008.
ISSN 0034-7280 (Sherpa/Romeo, fator de impacto)
Editor Soc Brasileira Oftalmologia
Extensão 165-171
Fonte http://dx.doi.org/10.1590/S0034-72802008000400002
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000259601300002
SciELO S0034-72802008000400002 (estatísticas na SciELO)
URI http://repositorio.unifesp.br/11600/45366

Mostrar registro completo




Arquivos deste item

Nome: S0034-72802008000400002.pdf
Tamanho: 106.7Kb
Formato: PDF
Descrição:
Visualizar/Abrir

Este item aparece na(s) seguinte(s) coleção(s)