Serum laminin in hepatosplenic human schistosomiasis

Serum laminin in hepatosplenic human schistosomiasis

Author Parise, Edison Roberto Autor UNIFESP Google Scholar
Leite-Mór, Marilisa Moraes Barros Autor UNIFESP Google Scholar
Rosa, Heitor Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Serum laminin level was measured in chronic hepatic schistosomiasis. A significant increase in the mean serum laminin levels was observed in patients with hepatosplenic (HS) schistosomiasis (2,57 +/- 0,83 U/ml), as compared to those in patients with the hepatointestinal (HI) form of the disease (1,38 +/- 0,45-U/ml) and in the control group (1,15 +/- 0,31 U/ml). In the HS patients there was a significant direct relation between serum laminin and percutaneous splenic pulp pressure (r = 0,68). These findings are compatible with an increased production of laminin in hepatosplenic schistosomiasis with may be related to the observed enlarged liver and spleen basement membranes in such disease.
Keywords HUMAN SCHISTOSOMIASIS
HEPATOSPLENIC FORM
SERUM LAMININ
Language English
Date 1992-01-01
Published in Memorias Do Instituto Oswaldo Cruz. Rio De Janeiro: Mem Inst Oswaldo Cruz, v. 87, n. supl 4, p. 127-128, 1992.
ISSN 0074-0276 (Sherpa/Romeo, impact factor)
Publisher Mem Inst Oswaldo Cruz
Extent 127-128
Origin http://dx.doi.org/10.1590/S0074-02761992000800018
Access rights Open access Open Access
Type Article
Web of Science ID WOS:A1992LB15000019
SciELO ID S0074-02761992000800018 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/44894

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