Clinical evolution of laryngeal granulomas: Treatment and prognosis

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dc.contributor.author Pontes, Paulo [UNIFESP]
dc.contributor.author De Biase, Noemi Grigoletto [UNIFESP]
dc.contributor.author Gadelha, Maria Emilia Cardoso
dc.date.accessioned 2018-06-18T10:54:46Z
dc.date.available 2018-06-18T10:54:46Z
dc.date.issued 1999-02-01
dc.identifier http://dx.doi.org/10.1097/00005537-199902000-00021
dc.identifier.citation Laryngoscope. Philadelphia: Lippincott Williams & Wilkins, v. 109, n. 2, p. 289-294, 1999.
dc.identifier.issn 0023-852X
dc.identifier.uri http://repositorio.unifesp.br/11600/44838
dc.description.abstract Objective/Hypothesis: To study the response to treatment by patients with granulomas not related to surgery, considering their respective causes. Methods: Retrospective study of larynx granulomas seen at the Institute da Laringe (Sao Paulo, Brazil) from June 1996, totaling 66 patients, being 20 (30,3%) diagnosed with gastroesophageal reflux syndrome, 22 (33,3%) due to vocal abuse, 15 (22,7%) to postorotracheal intubation, and 9 (13,6%) of idiopathic cause. Findings: Of the 66 patients diagnosed, 10 did not start the treatment, with only 56 being analyzed, 6 of whom later abandoned the treatment. The cause-oriented treatment showed 100% control in postintubation granulomas, In the cases of reflux and vocal abuse, the success rates when considering only the cause were 75% and 87.5%, respectively. In the cases of undefined cause, all were subjected to surgical removal with or without clinical or speech-therapy treatment; we attained only a 37.5% success rate in the first trial. Of these, after various unsuccessful rescue treatments, three which were treated with botulinum toxin type A had 100% resolution. The recurrence percentage varied according to the cause, being nonexistent in the postintubation cases, 21.4% in patients with reflux esophagitis, 35.2% in vocal abuse, and 62.5% in those of idiopathic etiology, Conclusion: Of the laryngeal granulomas, the best prognoses were given by the postintubation ones, whereas the worst were those of undefined cause. Those ascribed to gastroesophageal reflux and vocal abuse have a high resolution rate, although some cases need rescue procedures. en
dc.format.extent 289-294
dc.language.iso eng
dc.publisher Lippincott Williams & Wilkins
dc.relation.ispartof Laryngoscope
dc.rights Acesso aberto
dc.title Clinical evolution of laryngeal granulomas: Treatment and prognosis en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Inst Laringe
dc.description.affiliation Univ Fed Sao Paulo, Escola Paulista Med, Dept Otorhinolaryngol & Human Communicat Disorder, Sao Paulo, Brazil
dc.description.affiliation Inst Laringe, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Escola Paulista Med, Dept Otorhinolaryngol & Human Communicat Disorder, Sao Paulo, Brazil
dc.identifier.doi 10.1097/00005537-199902000-00021
dc.description.source Web of Science
dc.identifier.wos WOS:000078432500021



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