Reference Values for the Length and Area of the Fetal Corpus Callosum on 3-Dimensional Sonography Using the Transfrontal View

Reference Values for the Length and Area of the Fetal Corpus Callosum on 3-Dimensional Sonography Using the Transfrontal View

Author Araujo Junior, Edward Autor UNIFESP Google Scholar
Visentainer, Milena Autor UNIFESP Google Scholar
Simioni, Christiane Autor UNIFESP Google Scholar
Ruano, Rodrigo Google Scholar
Nardozza, Luciano Marcondes Machado Autor UNIFESP Google Scholar
Moron, Antonio Fernandes Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Objectives-The purpose of this study was to determine reference values for the length and area of the fetal corpus callosum between 20 and 33 weeks' gestation using 3-dimensional sonography.Methods-A cross-sectional study was performed in 293 healthy pregnant women between 20 and 33 weeks' gestation. The length and area of the corpus callosum were obtained via the transfontal view with the metopic suture as an acoustic window using 3-dimensional sonographic aquisitions. Linear and weighted polynomial regression models were used, which were adjusted by residual analysis and the R-2 determination coefficient. Intraobserver and interobserver reproducibilities were analyzed by an intraclass correlation coefficient.Results-The mean corpus callosum length +/- SD varied from 19.52 +/- 2.24 to 40.36 +/- 2.87 mm, whereas the mean area varied from 0.44 +/- 0.11 to 1.47 +/- 0.21 cm(2) at 20 and 33 weeks, respectively. The length and area were highly correlated with gestational age: corpus callosum length = -52.41 + 4.71 x gestational age - 0.06 x gestational age(2) (R-2 = 0.868); and corpus callosum area = -2.47 + 0.16 x gestational age -0.000037 x gestational age(2) (R-2 = 0.765). The intraobserver and interobserver reproducibties were excellent, with intraclass correlation coefficients of 0.98 and 0.94 for the length and 0.99 and 0.90 for the area, respectively.Conclusions-Reference values for the length and the area of the fetal corpus callosum between 20 and 33 weeks' gestation were determined with high reproducibility.
Keywords area
corpus callosum
fetus
length
reference value
3-dimensional sonography
transfrontal view
Language English
Date 2012-02-01
Published in Journal Of Ultrasound In Medicine. Laurel: Amer Inst Ultrasound Medicine, v. 31, n. 2, p. 205-212, 2012.
ISSN 0278-4297 (Sherpa/Romeo, impact factor)
Publisher Amer Inst Ultrasound Medicine
Extent 673-678
Origin http://dx.doi.org/10.7863/jum.2012.31.2.205
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000299717300005
URI http://repositorio.unifesp.br/11600/44777

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