Asymptomatic environmental enteropathy among slum-dwelling infants

Asymptomatic environmental enteropathy among slum-dwelling infants

Author Fagundes Neto, Ulysses Autor UNIFESP Google Scholar
Martins, Maria Ceci do Vale Autor UNIFESP Google Scholar
Lima, Fátima Maria Lindoso da Silva Autor UNIFESP Google Scholar
Patricio, Francy Reis da Silva Autor UNIFESP Google Scholar
Toledo, Maria Regina Fernandes de Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de Brasília (UnB)
Abstract Objective: We documented asymptomatic environmental enteropathy, which may occur in low socioeconomic populations, and which is manifested by bacterial proliferation in the upper portions of the small bower and by alterations in the digestive-absorptive capacity. Design: Forty asymptomatic infants (<1 year) of the Cidade Leonor slum in Sao Paulo,Brazil, were investigated for digestive-absorptive function, bacterial proliferation in the small bowel lumen, and jejunal morphology. They were compared with a control group of 8 well-nourished children from economically sound families. Results: Mean value of the D-xylose absorption test in the slum infants (21.0 +/- 10.0 mg%) was significantly lower than in controls (46.0 +/- 13.8 mg%) (p < 0.001). Colonic bacterial proliferation in the small bowel was identified in 25 (62.5%) of slum-dwelling infants. Grade II villous atrophy with inflammatory infiltration in the lamina propria was the most frequent alteration found. Conclusion: These data show that alterations in the microecology, function and morphology of the small intestine can occur even in the absence of diarrhea. Therefore, the absence of symptoms does not necessarily imply a healthy well-being among children living in a slum.
Keywords MALNUTRITION
BACTERIAL PROLIFERATION
MALABSORPTION
ENVIRONMENTAL CONTAMINATION
Language English
Date 1994-02-01
Published in Journal Of The American College Of Nutrition. New York: Amer Coll Nutrition, v. 13, n. 1, p. 51-56, 1994.
ISSN 0731-5724 (Sherpa/Romeo, impact factor)
Publisher Amer Coll Nutrition
Extent 180-185
Origin http://dx.doi.org/10.1080/07315724.1994.10718371
Access rights Closed access
Type Article
Web of Science ID WOS:A1994MU18100007
URI http://repositorio.unifesp.br/11600/44723

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