Action of propranolol on the atrial cardiomyocytes of rats submitted to cold stress

Action of propranolol on the atrial cardiomyocytes of rats submitted to cold stress

Author Lopes, Antonio Carlos Autor UNIFESP Google Scholar
Borrotchin, Luiz Autor UNIFESP Google Scholar
Sasso, Wilson da Silva Autor UNIFESP Google Scholar
Didio, Liberato John Alphonse Autor UNIFESP Google Scholar
Institution MED COLL OHIO
Universidade Federal de São Paulo (UNIFESP)
Abstract Subcellular changes of the atrial cardiomyocytes of rats caused by cold showed a) altered mitochondria with edema and lysis of crests; b) myofibrils with marked heterogeneity of patterns and ruptures, c) myofilaments disarrangement, partial necrosis and disintegration of filaments, d) lesser concentration of atrial granules in the perinuclear area. Atrial muscle fibers of propranolol-treated rats previously stressed by cold showed a marked decrease of the morphological alterations observed in the animals submitted to cold stress without propranolol protection.
Keywords PROPRANOLOL
COLD STRESS
ATRIAL CARDIOMYOCYTES
ELECTRON MICROSCOPY
MITOCHONDRIAL ALTERATIONS
MYOFIBRILS CHANGES
Language English
Date 1992-04-01
Published in Journal Of Submicroscopic Cytology And Pathology. Bologna: Editrice Compositori Bologna, v. 24, n. 2, p. 187-191, 1992.
ISSN 1122-9497 (Sherpa/Romeo, impact factor)
Publisher Editrice Compositori Bologna
Extent 187-191
Access rights Closed access
Type Article
Web of Science ID WOS:A1992HP07100006
URI http://repositorio.unifesp.br/11600/44710

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