Evaluation of depressive symptoms in patients with chronic renal failure

Evaluation of depressive symptoms in patients with chronic renal failure

Author Andrade, Carolina P. Autor UNIFESP Google Scholar
Cruz, Maria Carolina N. Google Scholar
Urrutia, Milton Google Scholar
Pereira, Otavio Google Scholar
Draibe, Sergio A. Google Scholar
Nogueira-Martins, Luiz A. Autor UNIFESP Google Scholar
Sesso, Ricardo Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Background: Although depression is the most commonly found psychiatric disorder in patients on chronic dialysis, its prevalence in earlier stages of chronic kidney disease (CKD) is not established. This study aims to investigate the prevalence of depression in patients with different stages of CKD and the factors associated with depressive affect.Methods: A total of 155 nondialytic patients with CKD on conservative therapy and 36 patients on hemodialysis treatment were studied. Depression was rated using the Beck Depression Inventory (BDI) and the Beck Depression Inventory-Short Form (BDI-SF). Functional capacity was evaluated using the Karnofsky Performance Scale, and clinical and sociodemographic variables were also investigated.Results: Using the BDI, depression was identified in 37.7% of the patients on conservative treatment and in 41.7% of those on hemodialysis (p=NS, not significant). The percentage of patients on conservative therapy with moderate or severe depression was higher when the BDI was used, compared with the BDI-SF (37.7% vs. 12.3%, p<0.001). No association was observed between depression and the stages of kidney disease. Among patients with CKD, depression was more prevalent among females (17.9%), patients of low income (54.2%), patients of social class D or E (47.4%), those living with friends or relatives (41.2%) and patients with poor functional capacity (p<0.001).Conclusions: We observed a high prevalence of depression in patients with CKD, but no significant difference was found between the stages of the disease. Depression was associated with sociodemographic characteristics and functional capacity.
Keywords Chronic kidney disease
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Date 2010-03-01
Published in Journal Of Nephrology. Milan: Wichtig Editore, v. 23, n. 2, p. 168-174, 2010.
ISSN 1121-8428 (Sherpa/Romeo, impact factor)
Publisher Wichtig Editore
Extent 168-174
Access rights Closed access
Type Article
Web of Science ID WOS:000276349400007
URI http://repositorio.unifesp.br/11600/44513

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