Gelatinase activity of exoantigens from virulent and non-virulent isolates of Paracoccidioides brasiliensis

Gelatinase activity of exoantigens from virulent and non-virulent isolates of Paracoccidioides brasiliensis

Author Vaz, CAC Google Scholar
Mackenzie, DWR Google Scholar
HEARN, V Google Scholar
Camargo, Z. P. Google Scholar
Singervermes, L. M. Google Scholar
Burger, E. Google Scholar
Calich, VLG Google Scholar
Institution CENT PUBL HLTH LAB
Universidade Federal de São Paulo (UNIFESP)
Abstract Differences in the occurrence of components with gelatinase activity were detected among four isolates of Paracoccidioides brasiliensis: Pb339 and Pb18 (highly virulent), and Pb265 and Pb18AV (very low virulence). Culture filtrates from these isolates were electrophoresed in substrate gels and tested for gelatinase activity. Pb339 showed three enzyme bands of apparent molecular masses: 43, 53 and 78 kDa; Pb18 had two bands, one at 59 kDa and another with molecular mass higher than 78 kDa. Isolate Pb18AV showed only one band at 78 kDa and Pb265 exhibited a component of molecular mass which failed to enter the separating gel.
Language English
Date 1994-01-01
Published in Journal Of Medical And Veterinary Mycology. Oxford: Blackwell Science Ltd, v. 32, n. 1, p. 65-69, 1994.
ISSN 0268-1218 (Sherpa/Romeo, impact factor)
Publisher Blackwell Science Ltd
Extent 65-69
Origin http://dx.doi.org/10.1080/02681219480000091
Access rights Closed access
Type Article
Web of Science ID WOS:A1994MY36500008
URI http://repositorio.unifesp.br/11600/44486

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