Salivary Cortisol, Alpha-Amylase and Heart Rate Variation in Response to Dental Treatment in Children

Salivary Cortisol, Alpha-Amylase and Heart Rate Variation in Response to Dental Treatment in Children

Author Furlan, N. F. Google Scholar
Gaviao, Maria Beatriz Duarte Google Scholar
Barbosa, T. S. Google Scholar
Nicolau, J. Google Scholar
Castelo, Paula Midori Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Universidade Estadual de Campinas (UNICAMP)
Abstract Objective. Anxiety and stress are usually related to the dental treatment situation. The objective was to investigate salivary cortisol and alpha-amylase levels (salivary biomarkers) and heart rate in children undergoing a minor dental procedure (dental prophylaxis). Study design. In total, 31 children (range 84-95 months) of both genders without caries or history of dental treatment/pain/trauma were selected. Three saliva samples were gathered: one prior to dental prophylaxis, one immediately after, and one ten minutes later Weight and height were assessed, and heart rate was evaluated prior to and during the procedure. Data were analyzed by correlation tests and t-test/Wikoxon (alpha=0.05). Results. Higher cortisol and amylase levels were observed before prophylaxis compared to afterward. Cortisol and amylase levels did not show a significant correlation, nor did salivary biomarkers and body mass index. However, heart rate and amylase levels showed a significant positive correlation. Conclusions. In the studied sample, certain anticipation of the dental treatment was observed because higher cortisol and amylase levels were observed before, rather than after, the event; moreover, a significant correlation between amylase levels and heart rate was observed. Thus, salivary biomarkers may be a valuable tool for evaluating anxiety-producing events, such as dental treatment, in children.
Keywords Alpha-amylases
Dental Prophylaxis
Heart rate
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number FAPESP: 2006/06338-0
FAPESP: 2007/05760-2
FAPESP: 2008/05103-4
Date 2012-09-01
Published in Journal Of Clinical Pediatric Dentistry. Birmingham: Journal Pedodontics Inc, v. 37, n. 1, p. 83-87, 2012.
ISSN 1053-4628 (Sherpa/Romeo, impact factor)
Publisher Journal Pedodontics Inc
Extent 83-87
Access rights Closed access
Type Article
Web of Science ID WOS:000312237200015

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