Research of Torque Teno Virus (TTV) in Serum and Total Blood of Brazilian Non-Human Primates and in Chicken Plasma (Gallus gallus domesticus) by the PCR N22 Region

Research of Torque Teno Virus (TTV) in Serum and Total Blood of Brazilian Non-Human Primates and in Chicken Plasma (Gallus gallus domesticus) by the PCR N22 Region

Alternative title Investigación de Torque teno virus (TTV) en Suero y Sangre de Primates No Humanos Brasileños y en Plasma de Pollo (Gallus gallus domesticus) por PCR en la Region N22
Author Catroxo, Marcia Helena Braga Autor UNIFESP Google Scholar
Nishiya, Anna Shoko Autor UNIFESP Google Scholar
Sabino, Ester Cerdeira Autor UNIFESP Google Scholar
Teixeira, P. S. Google Scholar
Petrella, S. Google Scholar
Milanelo, L. Google Scholar
Vieira, J. C. F. Autor UNIFESP Google Scholar
Diaz, Ricardo Sobhie Autor UNIFESP Google Scholar
Institution Biol Inst Sao Paulo
Universidade Federal de São Paulo (UNIFESP)
FundaCao Problood Homectr Sao Paulo
Universidade de São Paulo (USP)
Inst Adolfo Lutz Registro
Ecol Pk Tiete
Abstract Torque teno virus (TTV) is a recently discovered DNA virus that was originally isolated from a Japanese patient ( initials, TT) with post-transfusion hepatitis of unknown aetiology. TTV is an circular DNA virus classified recently together with related Torque teno minivirus, into a new genus called Anellovirus. Infection TTV has been detected in a range of non-human primates as well as domestic animals. The purpose of this study was to search TTV in the serum and total blood of Brazilian monkeys and in plasma of domestic chickens by seminested PCR of coding region (N22), followed by a genomic sequence and phylogenetic analysis. No serum sample was amplified. TTV DNA was detected in total blood from 3 (4%) out of 75 brown-capuchin ( Cebus apella) and from 1 (25%) out of 4 golden-headed lion-tamarin ( Leontopithecus chrysomelas). Phylogenetic analysis revealed that one sample showed similarity with one sequence of the cotton top tamarin ( Saguinus oedipus) (So-TTV2) and with one of the douroucoulis (Aotes trivirgatus) (At-TTV3). Two samples showed similarity with a human Torque Teno Mini Virus (TLMV). The other sample clustered with one sequence of the chimpanzee (Pt-TTV6) and with the human TTV strain TA278. The plasma chicken samples tested were all negative. The amino acid sequences reported in this study are the first obtained in Brazil from total blood of non-human primates naturally infected by TTV.
Keywords Torque teno virus
Non-humans primates
Coding region
Amino acid sequencing
Language English
Date 2008-06-01
Published in International Journal Of Morphology. Temuco: Soc Chilena Anatomia, v. 26, n. 2, p. 377-384, 2008.
ISSN 0717-9502 (Sherpa/Romeo, impact factor)
Publisher Soc Chilena Anatomia
Extent 377-384
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000261809200020
SciELO ID S0717-95022008000200020 (statistics in SciELO)

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