Cholesterolemia in colorectal cancer

Cholesterolemia in colorectal cancer

Author Forones, Nora Manoukian Autor UNIFESP Google Scholar
Falcao, Jeane Brito Autor UNIFESP Google Scholar
Mattos, D. Google Scholar
Barone, Boris Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract BAGKGROUND/AIMS: Colorectal cancer incidence is higher in developed countries. High fat intake is one of the risk factors. However, many studies observed lower cholesterol serum levels on diagnosis of colorectal cancer. The aim of this assay was to study the serum cholesterol levels in patients with colorectal cancer and compare these values with individuals of the same age and sex.METHODOLOGY: Cholesterol serum levels of 85 patients with colorecectal cancer were determined. Each of the patients with colorectal cancer were matched with an individual without cancer of the same age and sex. Total cholesterol concentrations were determined using an enzymatic colorimetric method.RESULTS: The mean serum of cholesterol was 183,4 for the colorectal group and 209.1 for the control group. This difference was statistically significant. This difference was more evident in patients with colon cancer and older than 60 years of age. There was no difference between the different Dukes' stage.CONCLUSIONS: Our study suggest an association between low blood cholesterol and colorectal cancer. We believe that the lower level of cholesterol observed in these patients is a consequence between the difference of colorectal carcinogenesis.
Keywords cholesterol serum levels
colorectal cancer
Language English
Date 1998-09-01
Published in Hepato-gastroenterology. Athens: H G E Update Medical Publ Ltd., v. 45, n. 23, p. 1531-1534, 1998.
ISSN 0172-6390 (Sherpa/Romeo, impact factor)
Publisher H G E Update Medical Publ Ltd.
Extent 1531-1534
Access rights Closed access
Type Article
Web of Science ID WOS:000077006600044
URI http://repositorio.unifesp.br/11600/43772

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