SERUM LEVELS OF ANDROSTANEDIOL GLUCURONIDE, TOTAL TESTOSTERONE, AND FREE TESTOSTERONE IN HIRSUTE WOMEN

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dc.contributor.author Khoury, Marcos Yorghi [UNIFESP]
dc.contributor.author Baracat, Edmund Chada [UNIFESP]
dc.contributor.author Pardini, Dolores Perovano [UNIFESP]
dc.contributor.author Vieira, Jose Gilberto Henriques [UNIFESP]
dc.contributor.author De Lima, Geraldo Rodrigues [UNIFESP]
dc.date.accessioned 2018-06-15T17:30:17Z
dc.date.available 2018-06-15T17:30:17Z
dc.date.issued 1994-07-01
dc.identifier http://www.fertstert.org/article/S0015-0282(16)56819-8/pdf
dc.identifier.citation Fertility And Sterility. Birmingham: Amer Soc Reproductive Medicine, v. 62, n. 1, p. 76-80, 1994.
dc.identifier.issn 0015-0282
dc.identifier.uri http://repositorio.unifesp.br/11600/43682
dc.description.abstract Objective: To determine the serum levels of androstanediol glucuronide (3 alpha-diol G), total T, and free T in hirsute and nonhirsute women.Design: Controlled clinical study.Patients: Hirsute women with oligomenorrhea, hirsute women with regular ovulatory cycles, and nonhirsute women with regular cycles were selected.Main Outcome Measure: Serum levels of 3 alpha-diol G, total T, and free T were measured in 8 hirsute with oligomenorrhea and 11 hirsute women with regular ovulatory cycles and compared with 20 nonhirsute women with regular cycles (control group). Serum 3 alpha-diol G was also measured during the follicular, periovulatory, and luteal phases in hirsute women with regular cycles.Results: Serum levels of 3 alpha-diol G did not change during the menstrual cycle, in addition we observed that there was no difference between the levels of 3 alpha-diol G, total T, and free T in hirsute women with regular cycles when compared with normal women. These three serum androgens were elevated only in the hirsute women with oligomenorrhea. Besides, there was better correlation between total T and free T (r = 0.81) than total T and 3 alpha-diol G (r = 0.49) or free T and 3 alpha-diol G (r = 0.66).Conclusion: The findings suggest that serum 3 alpha-diol G does not provide additional benefit as a marker of hirsutism than serum total or free T. en
dc.format.extent 76-80
dc.language.iso eng
dc.publisher Amer Soc Reproductive Medicine
dc.relation.ispartof Fertility And Sterility
dc.rights Acesso aberto
dc.subject ANDROSTANEDIOL GLUCURONIDE en
dc.subject TESTOSTERONE en
dc.subject HIRSUTISM en
dc.title SERUM LEVELS OF ANDROSTANEDIOL GLUCURONIDE, TOTAL TESTOSTERONE, AND FREE TESTOSTERONE IN HIRSUTE WOMEN en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation ESCOLA PAULISTA MED,DEPT GYNECOL,RUA JESUINO ARRUDA 666 APTO 53,BR-04532 SAO PAULO,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED,DEPT GYNECOL,RUA JESUINO ARRUDA 666 APTO 53,BR-04532 SAO PAULO,BRAZIL
dc.identifier.doi 10.1016/S0015-0282(16)56819-8
dc.description.source Web of Science
dc.identifier.wos WOS:A1994NT07200012



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