Autor |
Carvalho, R. D.
![]() Arida, Ricardo Mario ![]() ![]() Cavalheiro, Esper Abrão ![]() ![]() |
Instituição | Universidade Federal de São Paulo (UNIFESP) |
Resumo | Purpose: This study examined the effect of amygdala kindling development in Proechimys guayannensis rat, a common rodent of the Amazon basin.Methods: Adult male P. guayannensis animals (n = 43) and adult male Wistar rats (n = 14) were submitted to electrical amygdala kindling.Results: From 43 Proechimys rats submitted to the kindling process, only three animals reached stage 5 of kindling. During the kindling development (stages 4-5), these animals had behavioral alterations different from those observed in Wistar rats. A longer time spent in stages 1-3 and 5 and longer after discharge duration in stages 1-4 was observed in the Proechimys group compared with the Wistar group. The number of wet-dog shakes also was reduced in the Proechimys group during the kindling process.Conclusions: These findings suggest natural endogenous inhibitory mechanisms in this animal species. |
Assunto |
kindling
epilepsy Proechimys rats |
Idioma | Inglês |
Data | 2003-02-01 |
Publicado em | Epilepsia. Hoboken: Wiley-blackwell, v. 44, n. 2, p. 165-170, 2003. |
ISSN | 0013-9580 (Sherpa/Romeo, fator de impacto) |
Editor | Wiley-Blackwell |
Extensão | 165-170 |
Fonte |
|
Direito de acesso | Acesso aberto ![]() |
Tipo | Artigo |
Web of Science | WOS:000180917100005 |
URI | http://repositorio.unifesp.br/11600/43552 |
Arquivos | Tamanho | Formato | Visualização |
---|---|---|---|
Não existem arquivos associados a este item. |