Role of Physical Exercise as Complementary Treatment for Epilepsy and other Brain Disorders

Role of Physical Exercise as Complementary Treatment for Epilepsy and other Brain Disorders

Autor Arida, Ricardo Mario Autor UNIFESP Google Scholar
Scorza, Fulvio Alexandre Autor UNIFESP Google Scholar
Cavalheiro, Esper Abrão Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The impact of exercise on mental health, on cognition, brain function and brain structure as well as the possible underlying molecular systems important for maintaining neural function and plasticity has been extensively examined. Moreover, numerous studies have reinforced t the important and beneficial role of exercise for those with neurological disorders. This article reviews general aspects of physical exercise against neurodegenerative diseases and the relevant contributions of physical exercise programs as complementary therapy for epilepsy. We first give an overview of the plasticity induced by exercise in the damaged brain, the impact of exercise in reducing brain injury as well as in delaying onset of and decline in several neurodegenerative diseases. We address the relationship between epilepsy and exercise and report the neuroprotective and antiepileptogenic effects of exercise on epilepsy based on experimental and clinical studies. Overall, we conclude that physical or sport activities represent an exciting intervention that should be integrated with conventional therapy for the improvement of brain function and resistance to neurodegenerative diseases as well as a complementary non-pharmacological treatment of epilepsy.
Assunto Physical activity
exercise
brain injury
neurodegenerative diseases
epilepsy
seizure
neuroprotection
Idioma Inglês
Financiador Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
INNT (Brazil)
Data 2013-11-01
Publicado em Current Pharmaceutical Design. Sharjah: Bentham Science Publ Ltd, v. 19, n. 38, p. 6720-6725, 2013.
ISSN 1381-6128 (Sherpa/Romeo, fator de impacto)
Editor Bentham Science Publ Ltd
Extensão 6720-6725
Fonte http://dx.doi.org/10.2174/1381612811319380004
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000326344600004
URI http://repositorio.unifesp.br/11600/43468

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