Anti-Lewis alloimmunization: report of seven cases

Anti-Lewis alloimmunization: report of seven cases

Author Nardozza, Luciano Marcondes Machado Autor UNIFESP Google Scholar
Lobo, G. R. Autor UNIFESP Google Scholar
Moron, Antonio Fernandes Autor UNIFESP Google Scholar
Camano, Luiz Autor UNIFESP Google Scholar
Araujo, E. Autor UNIFESP Google Scholar
Guimarães Filho, Hélio Antonio Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: The purpose of this study was to investigate the perinatal results of seven pregnant women with anti-Lewis antibodies and evaluate the need to screen for these antigens during routine prenatal care. Setting: Sao Paulo University Hospital, Sao Paulo, Brazil. Population: 200 Rh-negative pregnant women with a positive indirect Coombs test, managed during a 6-year period. Methods: The charts of all patients were reviewed to collect pertinent data and the variables were analyzed. Main outcome measures: Indirect Coombs test titer, intrauterine transfusion, mode of delivery, gestational age at birth, birthweight, neonatal transfusion, duration of neonatal hospitalization and perinatal mortality. Results: All newborn infants were classified as adequate for gestational age at birth and none needed intrauterine or neonatal transfusions. All infants, except one, were discharged in good health on the third day after birth. Conclusions: Alloimmunized pregnancies (Levis antigens) have good perinatal results.
Keywords Anti-Le(a)
Alloimmunization in pregnancy
Antenatal screening
Hemolytic disease of the newborn
Language English
Date 2008-01-01
Published in Clinical And Experimental Obstetrics & Gynecology. Montreal: I R O G Canada, Inc, v. 35, n. 4, p. 311-312, 2008.
ISSN 0390-6663 (Sherpa/Romeo, impact factor)
Publisher I R O G Canada, Inc
Extent 311-312
Access rights Closed access
Type Article
Web of Science ID WOS:000261248400024

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