The Role of Metalloendopeptidases in Oropharyngeal Carcinomas Assessed by Tissue Microarray

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dc.contributor.author Ribeiro, Daniel Araki [UNIFESP]
dc.contributor.author Nascimento, Fábio Dupart [UNIFESP]
dc.contributor.author Fracalossi, Ana Carolina Cuzzuol [UNIFESP]
dc.contributor.author Noguti, Juliana [UNIFESP]
dc.contributor.author Oshima, Celina Tizuko Fujiyama [UNIFESP]
dc.contributor.author Ihara, Silvia Saiuli Miki [UNIFESP]
dc.contributor.author Franco, Marcello Fabiano de [UNIFESP]
dc.date.accessioned 2018-06-15T16:39:13Z
dc.date.available 2018-06-15T16:39:13Z
dc.date.issued 2011-11-01
dc.identifier https://cgp.iiarjournals.org/content/8/6/307.full.pdf
dc.identifier.citation Cancer Genomics & Proteomics. Athens: Int Inst Anticancer Research, v. 8, n. 6, p. 307-310, 2011.
dc.identifier.issn 1109-6535
dc.identifier.uri https://repositorio.unifesp.br/11600/43241
dc.description.abstract The goal of this study was to investigate the expression of some metalloendopeptidases in squamous cell carcinomas of the oropharynx as well as its relation to histological differentiation, staging of disease, and prognosis. Paraffin blocks from 21 primary tumors were obtained from archives of the Department of Pathology, Paulista Medical School, Federal University of Sao Paulo, UNIFESP/EPM. Immunohistochemistry was used to detect the expression of EP24.15 and EP24.16 by means of tissue microarrays. Expression of EP24.15 or EP24.16 was not correlated with the stage of disease, histopathological grading or recurrence in squamous cell carcinomas of the oropharynx. In summary, our results support the notion that EP24.15 and EP24.16 are expressed in carcinoma of the oropharynx; however, these do not appear to be suitable biomarkers for histological grading, disease stage or recurrence as depicted by tissue microarrays and immunohistochemistry. en
dc.format.extent 307-310
dc.language.iso eng
dc.publisher Int Inst Anticancer Research
dc.relation.ispartof Cancer Genomics & Proteomics
dc.rights Acesso aberto
dc.subject Squamous cell carcinomas en
dc.subject tissue microarray en
dc.subject metalloendopeptidases en
dc.title The Role of Metalloendopeptidases in Oropharyngeal Carcinomas Assessed by Tissue Microarray en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ Fed Sao Paulo, UNIFESP, Dept Biosci, BR-11060001 Santos, SP, Brazil
dc.description.affiliation Univ Fed Sao Paulo, UNIFESP, Dept Pathol, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, UNIFESP, Dept Biosci, BR-11060001 Santos, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, UNIFESP, Dept Pathol, BR-11060001 Santos, SP, Brazil
dc.description.source Web of Science
dc.identifier.wos WOS:000296994600003



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