Polycystic ovary syndrome: clinical and laboratory evaluation

Polycystic ovary syndrome: clinical and laboratory evaluation

Author Khoury, Marcos Yorghi Autor UNIFESP Google Scholar
Baracat, Edmund Chada Autor UNIFESP Google Scholar
Pardini, Dolores Perovano Autor UNIFESP Google Scholar
Haidar, Mauro Abi Autor UNIFESP Google Scholar
Motta, Eduardo Leme Alves da Autor UNIFESP Google Scholar
Lima, Geraldo Rodrigues De Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract OBJECTIVE: To evaluate clinically, and with laboratory, tests, women with polycystic ovary syndrome (PCO). PATIENTS: One hundred and twelve women with PCO were studied. METHODS: The following data was recorded: Current age; age at menarche; menstrual irregularity, occurrence of similar cases in the family; fertility, obstetric history; body mass index (BMI); and presence of hirsutism. Serum measurements of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, free testosterone, and dehydroepiandrosterone sulfate were taken. RESULTS: All patients presented either oligomenorrhea (31 percent), periods of secondary amenorrhea (9 percent), or both alterations (60 percent). The majority of the patients were infertile (75.6 percent). The LH/FSH ratio was higher than 2:1 in 55 percent of the patients and higher than 3:1 in 26.2 percent. The ultrasonographic aspect of the ovaries was considered to be normal in 31 percent. CONCLUSION: The main clinical feature of the PCO is the irregularity of menses since menarche, and that the laboratory tests would be important to exclude other disorders such as hyperprolactinemia or hyperandrogenemia caused by late-onset congenital adrenal hyperplasia.

OBJETIVOS: Avaliar clinica e laboratorialmente mulheres com a síndrome dos ovários policísticos (SOP). PACIENTES: Foram estudadas 112 mulheres com SOP. MÉTODOS: Avaliamos idade, idade da menarca, história menstrual, época do aparecimento da irregularidade menstrual, ocorrência de casos semelhantes na família, antecedentes obstétricos, índice de massa corpórea, e presença de hirsutismo. Foram realizadas as dosagens séricas de hormônio foliculo-estimulante (FSH), hormônio luteinizante (LH), prolactina, testosterona livre e de sulfato de dehidroepiandrosterona. RESULTADOS: Todas as mulheres apresentavam espaniomenorréia (31 percent), períodos de amenorréia secundária (9 percent) ou ambas alterações (60 percent). A maioria era infértil (75,6 percent). A relação LH/FSH era maior que 3 em 26,2 percent e maior que 2 em 55,0 percent das mulheres. O aspecto ultra-sonográfico dos ovários era normal em 31 percent das mulheres. CONCLUSÃO: A principal característica clínica da SOP é a irregularidade menstrual desde a menarca e os exames de laboratório seriam importantes para afastar outras patologias como as síndromes hiperprolactinêmicas ou as deficiências enzimáticas tardias da supra-renal.
Keywords Polycystic Ovary syndrome
Secondary amenorrhea
Language English
Date 1996-08-01
Published in São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 114, n. 4, p. 1222-1225, 1996.
ISSN 1516-3180 (Sherpa/Romeo)
Publisher Associação Paulista de Medicina - APM
Extent 1222-1225
Origin http://dx.doi.org/10.1590/S1516-31801996000400006
Access rights Open access Open Access
Type Article
SciELO ID S1516-31801996000400006 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/431

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