BLOOD-GLUCOSE AND INSULIN-RESPONSE TO INTRAVENOUS GLUCOSE BY PATIENTS WITH CHRONIC CHAGAS-DISEASE AND ALCOHOLISM

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dc.contributor.author Oliveira, LCM
dc.contributor.author Juliano, Yara [UNIFESP]
dc.contributor.author Novo, Neil Ferreira [UNIFESP]
dc.contributor.author Neves, Manoel Martins das [UNIFESP]
dc.date.accessioned 2018-06-15T14:28:04Z
dc.date.available 2018-06-15T14:28:04Z
dc.date.issued 1993-11-01
dc.identifier.citation Brazilian Journal Of Medical And Biological Research. Sao Paulo: Assoc Bras Divulg Cientifica, v. 26, n. 11, p. 1187-1190, 1993.
dc.identifier.issn 0100-879X
dc.identifier.uri http://repositorio.unifesp.br/11600/43032
dc.description.abstract Blood glucose and insulin responses to intravenous glucose 500 mg/kg in a group of alcoholic chagasic patients (Group I, N = 15) were assessed and compared to those of a group of patients with Chagas' disease without alcoholism (Group II, N = 16), a group of alcoholics without Chagas' disease (Group III, N = 22), and a group of non-alcoholics without Chagas' disease (Group IV, N = 15). Determinations of serum glucose and insulin were done under fasting conditions, 5 and 10 min after the injection of 50% glucose. There was no difference in mean serum glucose levels between groups. Mean serum insulin levels at times 5 and 10 min and for the total integrated response were lower (P<0.05) in Groups I and II as compared to Group IV; at time 10 min the mean was lower (P<0.05) in Group III as compared to Group IV. There was a nonsignificant trend for a lower insulinemic response in Group I as compared to Group II. These data suggest denervation of or injury to pancreatic B cell by Chagas' disease. en
dc.format.extent 1187-1190
dc.language.iso eng
dc.publisher Assoc Bras Divulg Cientifica
dc.relation.ispartof Brazilian Journal Of Medical And Biological Research
dc.rights Acesso restrito
dc.subject BLOOD GLUCOSE en
dc.subject BLOOD INSULIN en
dc.subject ALCOHOLISM en
dc.subject AMERICAN TRYPANOSOMIASIS en
dc.subject CHAGAS DISEASE en
dc.title BLOOD-GLUCOSE AND INSULIN-RESPONSE TO INTRAVENOUS GLUCOSE BY PATIENTS WITH CHRONIC CHAGAS-DISEASE AND ALCOHOLISM en
dc.type Artigo
dc.contributor.institution Universidade Federal de Uberlândia (UFU)
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation UNIV FED UBERLANDIA,CURSO MED,DEPT CLIN MED,BR-38400902 UBERLANDIA,MG,BRAZIL
dc.description.affiliation ESCOLA PAULISTA MED,DISCIPLINA BIOESTATIST,BR-04023062 SAO PAULO,SP,BRAZIL
dc.description.affiliation ESCOLA PAULISTA MED,DISCIPLINA GASTROENTEROL CLIN,BR-04023062 SAO PAULO,SP,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED,DISCIPLINA BIOESTATIST,BR-04023062 SAO PAULO,SP,BRAZIL
dc.description.affiliationUnifesp ESCOLA PAULISTA MED,DISCIPLINA GASTROENTEROL CLIN,BR-04023062 SAO PAULO,SP,BRAZIL
dc.description.source Web of Science
dc.identifier.wos WOS:A1993MG75900006



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