EFFECTS OF WHOLE-BODY X-IRRADIATION ON THE PERIPHERAL-BLOOD OF PRIMATE CEBUS-APELLA

EFFECTS OF WHOLE-BODY X-IRRADIATION ON THE PERIPHERAL-BLOOD OF PRIMATE CEBUS-APELLA

Author Egami, Mizue Imoto Autor UNIFESP Google Scholar
Segreto, Camilo Autor UNIFESP Google Scholar
Kerbauy, José Autor UNIFESP Google Scholar
Juliano, Yara Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The effects of ionizing radiation on the peripheral blood elements of primate Cebus apella were examined after a single 25.8 mC/kg (100 R) dose of whole-body X-ray. We determined the number of white blood cells, neutrophils, eosinophils, basophils, lymphocytes, monocytes and erythrocytes up to 90 days after exposure of 5 animals. Hemoglobin content and microhematocrit were also determined. Under these experimental conditions, the total number of leukocytes was reduced from 9440/mm3 to 5660/mm3 on day 6, mainly because of a decrease in the lymphocyte population from 5843.2/mm3 to 2349.0/mm3 on day 6. No significant differences were observed in the values of erythrocytes, neutrophils, eosinophils, basophils, monocytes, hemoglobin content and microhematocrit. All hematological parameters studied returned to normal values by day 90 after a single irradiation dose of 100 R.
Keywords BLOOD CELL CHANGES
PRIMATES
X-RAYS
Language English
Date 1991-01-01
Published in Brazilian Journal Of Medical And Biological Research. Sao Paulo: Assoc Bras Divulg Cientifica, v. 24, n. 3, p. 271-274, 1991.
ISSN 0100-879X (Sherpa/Romeo, impact factor)
Publisher Assoc Bras Divulg Cientifica
Extent 271-274
Access rights Closed access
Type Article
Web of Science ID WOS:A1991FJ38600005
URI http://repositorio.unifesp.br/11600/43003

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