REGIONAL COOLING FOR REDUCING BRAIN TEMPERATURE AND INTRACRANIAL PRESSURE

REGIONAL COOLING FOR REDUCING BRAIN TEMPERATURE AND INTRACRANIAL PRESSURE

Alternative title Resfriamento cerebral regional para redução da temperatura e pressão intracraniana
Author Forte, Luis Vicente Autor UNIFESP Google Scholar
Peluso, Cassio Morano Autor UNIFESP Google Scholar
Prandini, Mirto Nelso Autor UNIFESP Google Scholar
Godoy, Roberto Google Scholar
Rojas, Salomon Soriano Ordinola Google Scholar
Institution Hosp Sao Joaquim
Hosp Meridional
Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: To evaluate the effectiveness of regional cooling for reducing brain temperature (BrTe) and intracranial pressure (ICP) in patients where conventional clinical treatment has failed. Method: Regional cooling was carried out using ice bags covering the area of the craniectomy (regional method) in 23 patients. The BrTe and ICP were determined using a fiber optic sensor. Thirteen patients (56.52%) were female. The ages ranged from 16 to 83 years (mean of 48.9). The mean APACHE II score was 25 points (11-35). The patients were submitted, on mean, to 61.7 hours (20-96) of regional cooling. Results: There was a significant reduction in mean BrTe (p<0.0001-from 37.1 degrees C to 35.2 degrees C) and mean ICP (p=0.0001-from 28 mmHg to 13 mmHg). Conclusion: Our results suggest that mild brain hypothermia induced by regional cooling was effective in the control of ICP in patients who had previously undergone decompressive craniectomy.
Keywords intracranial hypertension
intracranial pressure
cerebral hypothermia
brain edema
brain injuries
Language English
Date 2009-06-01
Published in Arquivos De Neuro-psiquiatria. Sao Paulo Sp: Assoc Arquivos Neuro- Psiquiatria, v. 67, n. 2B, p. 480-487, 2009.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Assoc Arquivos Neuro- Psiquiatria
Extent 480-487
Origin http://dx.doi.org/10.1590/S0004-282X2009000300019
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000268140200019
SciELO ID S0004-282X2009000300019 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/42749

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