Parathyroid carcinoma and hungry bone syndrome

Parathyroid carcinoma and hungry bone syndrome

Título alternativo Carcinoma de paratiroide e fome óssea
Autor Ohe, Monique Nakayama Autor UNIFESP Google Scholar
Santos, Rodrigo Oliveira Autor UNIFESP Google Scholar
Hojaij, Flavio Carneiro Autor UNIFESP Google Scholar
Neves, Murilo Catafesta Autor UNIFESP Google Scholar
Kunii, Ilda Sizue Autor UNIFESP Google Scholar
Orlandi, Denise Autor UNIFESP Google Scholar
Valle, Luisa Autor UNIFESP Google Scholar
Martins, Carla Autor UNIFESP Google Scholar
Janovsky, Carolina Autor UNIFESP Google Scholar
Ferreira, Rimarcs Gomes Autor UNIFESP Google Scholar
Delcelo, Roseane Autor UNIFESP Google Scholar
Domingos, Ana Maria Autor UNIFESP Google Scholar
Abrahão, Márcio Autor UNIFESP Google Scholar
Cervantes, Onivaldo Autor UNIFESP Google Scholar
Lazaretti-Castro, Marise Autor UNIFESP Google Scholar
Vieira, Jose Gilberto Henriques Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo We hereby report two patients with parathyroid carcinoma presenting extremely high calcium and PTH levels, severe bone disease, and palpable neck mass at diagnosis. They both underwent parathyroidectomy, and one of them evolved to lung metastasis. Important hypocalcemia was observed after surgery in both: after parathyroidectomy in one patient, and only after surgical removal of the metastasis in the other. Both required intravenous calcium replacement, thus revealing hungry bone syndrome (HBS). HBS usually reflects rapid mineralization after correction of hyperparathyroidism. The more severe the bone disease before surgery, the more prone the patient is to HBS after surgery. Despite being an unfavorable outcome, HBS state suggests that surgical removal of hypersecretory parathyroid tissue was accomplished. In this study, HBS was observed in both patients, who presented severe bone disease prior to surgery. HBS would be expected post-operatively in successful parathyroid carcinoma removal. Arq Bras Endocrinol Metab. 2013; 57(1):79-86
Idioma Inglês
Data 2013-02-01
Publicado em Arquivos Brasileiros De Endocrinologia E Metabologia. Rio De Janeiro, Rj: Sbem-soc Brasil Endocrinologia & Metabologia, v. 57, n. 1, p. 79-86, 2013.
ISSN 0004-2730 (Sherpa/Romeo, fator de impacto)
Editor Sbem-soc Brasil Endocrinologia & Metabologia
Extensão 79-86
Fonte http://dx.doi.org/10.1590/S0004-27302013000100011
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000315334000011
SciELO S0004-27302013000100011 (estatísticas na SciELO)
URI http://repositorio.unifesp.br/11600/42711

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