Neuromyelitis optica: brain abnormalities in a Brazilian cohort

Neuromyelitis optica: brain abnormalities in a Brazilian cohort

Alternative title Neuromielite óptica: alterações encefálicas em pacientes brasileiros
Author Bichuetti, Denis Bernardi Autor UNIFESP Google Scholar
Rivero, René Leandro Magalhães Autor UNIFESP Google Scholar
Oliveira, Daniel May Autor UNIFESP Google Scholar
Souza, Nilton Amorin de Autor UNIFESP Google Scholar
Abdala, Nitamar Autor UNIFESP Google Scholar
Oliveira, Enedina Maria Lobato de Autor UNIFESP Google Scholar
Gabbai, Alberto Alain Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Schering do Brasil
Abstract Neuromyelitis optica (NMO) is a demyelinating disease consisting of relapsing-remitting optic neuritis and myelitis with a more severe course than Multiple Sclerosis. Recently, it has been shown that almost 50% of patients with NMO can have brain magnetic resonance imaging (MRI) abnormalities. We report on six Brazilian patients with NMO, fulfilling the 1999 Wingerchuck criteria for this disease, with abnormal brain MRI and discuss their clinical and radiological features.

Neuromielite óptica (NMO) é doença desmielinizante, remitente-recorrente, com acometimento predominante dos nervos ópticos e medula espinal e uma evolução mais grave comparada à esclerose múltipla. Estudos recentes demonstraram que até 50% dos pacientes com NMO podem apresentar lesões encefálicas à ressonância magnética (RM). Relatamos seis pacientes brasileiros com NMO, que satisfazem os critérios diagnósticos de Wingerchuck (1999) para NMO, com alterações encefálicas em RM de encéfalo e discutimos seus dados clínicos e de imagem.
Keywords neuromyelitis optica
brain abnormalities
MRI
neuromielite óptica
erações encefálicas
ressonância magnética
Language English
Date 2008-03-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 66, n. 1, p. 1-4, 2008.
ISSN 0004-282X (Sherpa/Romeo)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 1-4
Origin http://dx.doi.org/10.1590/S0004-282X2008000100001
Access rights Open access Open Access
Type Article
SciELO ID S0004-282X2008000100001 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/4260

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