Gap junctions between mast cells and fibroblasts in the developing avian eye

Gap junctions between mast cells and fibroblasts in the developing avian eye

Author Oliani, Sonia Maria Autor UNIFESP Google Scholar
Girol, Ana Paula Autor UNIFESP Google Scholar
Smith, Ricardo Luiz Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Mast cells are present in the eye of chick embryos from the 14th day onward, displaying metachromatic granules, mainly in the iris anterior surface and pectinate ligament, Ultrastructurally these cells show electron-dense granules and a few thin and short cytoplasmic projections in close contact with fibroblasts. Sometimes these contacts are extensive, with long fibroblast projections partially involving the mast cells. Gap junctions between mast cells and fibroblasts are observed only in the eyes of 16- and 20-day-old embryos. These intercellular specializations are represented by a close apposition of cytoplasmic membranes with an extension up to 300 nm. Gap junctions between mast cells and fibroblasts were not observed previously in vivo or in vitro, although in vitro studies have shown that a number of functionally critical interactions may occur between these cells. Our morphological findings suggest that, in vivo, fibroblasts interact with mast cells and may influence their maturation.
Keywords mast cell
fibroblast
gap junction
eye
development
chick
Language English
Date 1995-01-01
Published in Acta Anatomica. Basel: Karger, v. 154, n. 4, p. 267-271, 1995.
ISSN 0001-5180 (Sherpa/Romeo, impact factor)
Publisher Karger
Extent 267-271
Origin http://dx.doi.org/10.1159/000147778
Access rights Closed access
Type Article
Web of Science ID WOS:A1995UM16700003
URI http://repositorio.unifesp.br/11600/41970

Show full item record




File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account