Neuromyelitis optica spectrum disorders: beyond longitudinally extensive transverse myelitis

Neuromyelitis optica spectrum disorders: beyond longitudinally extensive transverse myelitis

Autor Lemos, M. D. Autor UNIFESP Google Scholar
Carvalho, G. B. S. Autor UNIFESP Google Scholar
Carvalho, R. S. Autor UNIFESP Google Scholar
Bichuetti, D. B. Autor UNIFESP Google Scholar
Oliveira, E. M. L. de Autor UNIFESP Google Scholar
Abdala, Nitamar Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo AIM: To describe the neuroradiological features and their prevalence in patients with neuromyelitis optica (NMO).MATERIALS and METHODS: Two neuroradiologists independently reviewed 35 spinal cord and 37 brain MRI studies from patients with NMO. the examinations were analysed for the presence of lesion, topography, enhancement, and brain lesions suggestive of multiple sclerosis and/or NMO.RESULTS: Seventy percent of the spinal cord lesions involved over three or more vertebral segments. Seventy-eight percent of brain scans were abnormal, and the most prevalent findings were non-specific foci of T2 hyperintensities in the cerebral white matter (55%) and brainstem lesions (52%). One patient had lesions disseminated in space compatible with multiple sclerosis according to 2010 revised McDonald criteria. Brain lesions suggestive of NMO occurred at least once in 17 (59%) patients.CONCLUSION: Spinal cord lesions were often longitudinally extensive and brain lesions-were common, with the majority of patients having at least one distinctive NMO lesion. (C) 2015 the Royal College of Radiologists. Published by Elsevier B.V. All rights reserved.
Idioma Inglês
Financiador Bayer Health Care
Merck Serono
TEVA
Data 2015-06-01
Publicado em Clinical Radiology. London: W B Saunders Co Ltd, v. 70, n. 6, p. 630-637, 2015.
ISSN 0009-9260 (Sherpa/Romeo, fator de impacto)
Editor W B Saunders Co Ltd
Extensão 630-637
Fonte http://dx.doi.org/10.1016/j.crad.2015.02.016
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000355062200010
URI http://repositorio.unifesp.br/handle/11600/39124

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