Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags

Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags

Autor Gentil, Luciana Girotto Autor UNIFESP Google Scholar
Lasakosvitsch, Fernanda Autor UNIFESP Google Scholar
Franco da Silveira, José Autor UNIFESP Google Scholar
Santos, Márcia Regina Machado dos Autor UNIFESP Google Scholar
Barbiéri, Clara Lúcia Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any other sequences in database and 68% presented significant similarities to known genes. The chromosome localization of some L. (L.) amazonensis ESTs was also determined in L. (L.) amazonensis and L. (L.) major. The characterization of these ESTs is suitable for the genome physical mapping, as well as for the identification of genes encoding cysteine proteinases implicated with protective immune responses in leishmaniasis.
Assunto Leishmania (Leishmania) amazonensis
amastigotes
cDNA library
Idioma Inglês
Data 2007-09-01
Publicado em Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 102, n. 6, p. 707-711, 2007.
ISSN 0074-0276 (Sherpa/Romeo)
Editor Instituto Oswaldo Cruz, Ministério da Saúde
Extensão 707-711
Fonte http://dx.doi.org/10.1590/S0074-02762007005000065
Direito de acesso Acesso aberto Open Access
Tipo Artigo
SciELO S0074-02762007000600008 (estatísticas na SciELO)
URI http://repositorio.unifesp.br/handle/11600/3894

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