Influence of Microelement Concentration on the Intensity of Alcohol Withdrawal Syndrome

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dc.contributor.author Prior, Pedro Luis [UNIFESP]
dc.contributor.author Vaz, Marta Jezierski
dc.contributor.author Ramos, Anna Carolina [UNIFESP]
dc.contributor.author Fernandes Galduroz, Jose Carlos [UNIFESP]
dc.date.accessioned 2016-01-24T14:40:12Z
dc.date.available 2016-01-24T14:40:12Z
dc.date.issued 2015-03-01
dc.identifier http://dx.doi.org/10.1093/alcalc/agu094
dc.identifier.citation Alcohol and Alcoholism. Oxford: Oxford Univ Press, v. 50, n. 2, p. 152-156, 2015.
dc.identifier.issn 0735-0414
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/38852
dc.description.abstract Aims: To establish a nutritional and constitutional profile concerning the micronutrient plasma concentration of patients who suffer from AWS. Method: Observational case control study to determine whether patients who exhibited symptoms of AWS (N = 60) had micronutrient plasmatic concentration deficiencies when compared with healthy controls (N = 34). Results: There were statistically significant differences between the concentrations of nutrients that are correlated with glutamate hyperactivity (zinc, magnesium and folate/vitamin B12/homocysteine). Conclusion: Evidence from literature and our experiment suggests that brain activity, especially the glutamatergic system, might be directly involved in micronutrient concentrations. Therefore, their supplementation to the AWS patient might improve symptom evolution. en
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorship Associacao Fundo de Incentivo a Pesquisa (AFIP)
dc.description.sponsorship Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent 152-156
dc.language.iso eng
dc.publisher Oxford Univ Press
dc.relation.ispartof Alcohol and Alcoholism
dc.rights Acesso restrito
dc.title Influence of Microelement Concentration on the Intensity of Alcohol Withdrawal Syndrome en
dc.type Artigo
dc.rights.license http://www.oxfordjournals.org/access_purchase/self-archiving_policyb.html
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Ctr Referencia Tratamento Alcool Tabaco & Outras
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Psychobiol, São Paulo, Brazil
dc.description.affiliation Ctr Referencia Tratamento Alcool Tabaco & Outras, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Psychobiol, São Paulo, Brazil
dc.description.sponsorshipID FAPESP: 2012/06731-4
dc.identifier.doi 10.1093/alcalc/agu094
dc.description.source Web of Science
dc.identifier.wos WOS:000352161800006



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