Influence of Intestinal Microbiota on Body Weight Gain: a Narrative Review of the Literature

Influence of Intestinal Microbiota on Body Weight Gain: a Narrative Review of the Literature

Author Cardinelli, Camila S. Google Scholar
Sala, Priscila C. Google Scholar
Alves, Claudia C. Autor UNIFESP Google Scholar
Torrinhas, Raquel S. Google Scholar
Waitzberg, Dan L. Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract In recent decades, experimental and clinical studies have associated the development of obesity with the composition of the gut microbiota. Mechanisms potentially involved in the contribution of gut microbiota to body weight gain include changes in energy extraction from the diet and the modulation of lipid metabolism, endocrine functions, and the immune system. the host's specific genetic heritage, the type and amount of food intake, chronic inflammation, reduced body energy expenditure, and exposure to obesogenic pollutants are also potential contributing factors. the pathophysiological processes involved in the relationship between gut microbiota and obesity are not fully understood, and further studies are needed to establish whether differences in gut bacterial diversity between obese and normal body weight individuals are the cause or a consequence of obesity.
Keywords Gutmicrobiota
Energy capture
Genetic factors
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number FAPESP: FAPESP 2011/09612-3
Date 2015-02-01
Published in Obesity Surgery. New York: Springer, v. 25, n. 2, p. 346-353, 2015.
ISSN 0960-8923 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 346-353
Access rights Closed access
Type Review
Web of Science ID WOS:000348111000023

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