Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease

Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease

Author Aoike, Danilo Takashi Autor UNIFESP Google Scholar
Baria, Flavia Autor UNIFESP Google Scholar
Kamimura, Maria Ayako Autor UNIFESP Google Scholar
Ammirati, Adriano Autor UNIFESP Google Scholar
Mello, Marco Tulio de Autor UNIFESP Google Scholar
Cuppari, Lilian Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Home-based exercise has been shown to provide benefits in terms of physical capacity in the general population, but has been scarcely investigated in patients with chronic kidney disease (CKD).To evaluate the impact of a home-based aerobic training on the cardiopulmonary and functional capacities of overweight non-dialysis-dependent patients with CKD (NDD-CKD).Twenty-nine sedentary patients (55.1 +/- A 11.6 years, BMI = 31.2 +/- A 6.1 kg/m(2), eGFR = 26.9 +/- A 17.4 mL/min/1.73 m(2)) were randomly assigned to a home-based exercise group (n = 14) or to a control group (n = 15) that remained without performing exercise. Aerobic training was performed three times per week for 12 weeks. A cardiopulmonary exercise test, functional capacity and clinical parameters were evaluated.A significant increase, ranging from 8.3 to 17 %, was observed in the cardiopulmonary capacity parameters, such as maximal ventilation (p = 0.005), VO2peak (p = 0.049), ventilatory threshold (p = 0.040) and respiratory compensation point (p < 0.001), of the exercise group. A simultaneous improvement in the functional capacity tests [6-min walk test (p < 0.001), time up and go test (p < 0.001), arm curl test (p < 0.001), sit and stand test (p < 0.001), 2-min step test (p < 0.001) and back scratch test (p = 0.042)] was also found in patients who were submitted to the exercise. Exercised patients experienced a decrease in systolic and diastolic blood pressure, average 10.6 % (p < 0.001) and 9.2 % (p = 0.007), respectively, and a trend toward improved renal function (p = 0.1). No change in any parameter was found in the control group during the follow-up.The home-based aerobic exercise program was feasible, safe and effective for the improvement in the cardiopulmonary and functional capacities of overweight NDD-CKD patients.
Keywords Chronic kidney disease
Home-based aerobic exercise
Physical function
Obesity
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Oswaldo Ramos Foundation
Centro de Estudos em Psicobiologia e Exercicio/Associacao de Fundo e Incentivo a Pesquisa
Grant number FAPESP: 2009/147860
Date 2015-02-01
Published in International Urology and Nephrology. Dordrecht: Springer, v. 47, n. 2, p. 359-367, 2015.
ISSN 0301-1623 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 359-367
Origin http://dx.doi.org/10.1007/s11255-014-0894-8
Access rights Closed access
Type Article
Web of Science ID WOS:000348995500023
URI http://repositorio.unifesp.br/handle/11600/38682

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