Bioactivity behaviour of nano-hydroxyapatite/freestanding aligned carbon nanotube oxide composite

Bioactivity behaviour of nano-hydroxyapatite/freestanding aligned carbon nanotube oxide composite

Autor Siqueira, Idalia A. W. B. Google Scholar
Oliveira, Ciliana A. G. S. Google Scholar
Zanin, Hudson Google Scholar
Grinet, Marco A. V. M. Google Scholar
Granato, Alessandro E. C. Autor UNIFESP Google Scholar
Porcionatto, Marimelia A. Autor UNIFESP Google Scholar
Marciano, Fernanda R. Google Scholar
Lobo, Anderson O. Google Scholar
Instituição Univ Vale Paraiba
Universidade Federal de São Paulo (UNIFESP)
Resumo Bioactive and low cytotoxic three dimensional nano-hydroxyapatite (nHAp) and aligned carbon nanotube oxide (a-CNTO) composite has been investigated. First, freestanding aligned carbon nanotubes porous scaffold was prepared by large-scale thermal chemical vapour deposition and functionalized by oxygen plasma treatment, forming a-CNTO. the a-CNTO was covered with plate-like nHAp crystals prepared by in situ electrodeposition techniques, forming nHAp/a-CNTO composite. After that nHAp/a-CNTO composite was immersed in simulated body fluid for composite consolidation. This novel nanobiomaterial promotes mesenchymal stem cell adhesion with the active formation of membrane projections, cell monolayer formation and high cell viability.
Idioma Inglês
Financiador Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Número do financiamento FAPESP: 2011/17877-7
FAPESP: 2013/07696-0
FAPESP: 2011/20345-7
FAPESP: 2014/02163-7
CNPq: 474090/2013-2
CNPq: 202439/2012-7
CNPq: 404646/2012-3
Data de publicação 2015-02-01
Publicado em Journal of Materials Science-materials in Medicine. Dordrecht: Springer, v. 26, n. 2, 10 p., 2015.
ISSN 0957-4530 (Sherpa/Romeo, fator de impacto)
Publicador Springer
Extensão 10
Fonte http://dx.doi.org/10.1007/s10856-015-5450-2
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000349402400052
Endereço permanente http://repositorio.unifesp.br/handle/11600/38680

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