Green Coffea arabica L. seed oil influences the stability and protective effects of topical formulations

Green Coffea arabica L. seed oil influences the stability and protective effects of topical formulations

Author Wagemaker, Tais A. L. Google Scholar
Silva, Silas A. M. Autor UNIFESP Google Scholar
Leonardi, Gislaine R. Autor UNIFESP Google Scholar
Maia Campos, Patricia M. B. G. Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Abstract Green Coffea arabica L. seed oil (GCO) has been used as an active ingredient in many skin care products, due to its properties as an emollient, improver of skin hydration and absorbent of UVB radiation. However, to obtain a stable, effective and pleasant formulation containing variable amounts of GCO it is necessary to know specific chemical characteristics of the combined ingredients. Thus, this study evaluated rheological behavior, presence of liquid crystals (LCs) and skin protective effects of GCO-containing formulations aiming to correlate these parameters with GCO concentrations by using a principal component analysis (PCA). Formulations containing GCO or not (0-15%) were submitted to physical stability assays by determinations of rheological behavior after 90 days storage, detection of LCs by polarized light microscopy and in vitro determination of the sun protection factor (SPF). in vivo protective effects in mice were evaluated with biophysical techniques and histological analysis. Data were correlated using PCA. Despite the low SPF values, GCO addition to formulations resulted in significant and proportional increases of these values. It is concluded that formulation stability and skin protective properties are influenced by GCO but desirable effects are only possible when GCO is present in high concentrations. (C) 2014 Elsevier B.V. All rights reserved.
Keywords Green coffee oil
Rheological behavior
Liquid crystals
Biophysical techniques
Sun protection factor
PCA
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number FAPESP: 2009/14031-0
Date 2015-01-01
Published in Industrial Crops and Products. Amsterdam: Elsevier B.V., v. 63, p. 34-40, 2015.
ISSN 0926-6690 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 34-40
Origin http://dx.doi.org/10.1016/j.indcrop.2014.09.045
Access rights Closed access
Type Article
Web of Science ID WOS:000347499000005
URI http://repositorio.unifesp.br/handle/11600/38588

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