Restless Genital Syndrome in Parkinson Disease

Restless Genital Syndrome in Parkinson Disease

Author Aquino, Camila C. Autor UNIFESP Google Scholar
Mestre, Tiago Google Scholar
Lang, Anthony E. Google Scholar
Institution Toronto Western Hosp
Universidade Federal de São Paulo (UNIFESP)
Univ Ottawa
Abstract IMPORTANCE Symptoms in the genital region, such as pain, discomfort, tingling, and burning sensations, have rarely been reported in Parkinson disease (PD), and the previous cases were attributed to nonmotor off symptoms. We report a patient with PD and severe genital discomfort unrelated to motor fluctuations but compatible with restless genital syndrome.OBSERVATIONS A 65-year-old woman with PD experienced a disabling discomfort in her pelvis and genital region for 3 years. the episodes occurred in the evening and were triggered by sitting or lying down for a period. Gynecological investigation was unrevealing. She experienced improvement with a low dose of a dopamine agonist.CONCLUSION and RELEVANCE Restless genital syndrome is a rare disorder that can be a source of distress and disability. in patients with PD, restless genital syndrome should be included in the differential diagnosis of genital symptoms and restlessness, along with nonmotor wearing off and akathisia. A detailed clinical history is essential for this diagnosis and treatment with dopamine agonists can provide benefit.
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Brain Canada
Canadian Institutes of Health Research
Edmond J. Safra Foundation
Michael J. Fox Foundation
National Parkinson Foundation
Parkinson Society Canada
Tourette Syndrome Association
W. Garfield Weston Foundation
Date 2014-12-01
Published in Jama Neurology. Chicago: Amer Medical Assoc, v. 71, n. 12, p. 1559-1561, 2014.
ISSN 2168-6149 (Sherpa/Romeo, impact factor)
Publisher Amer Medical Assoc
Extent 1559-1561
Access rights Closed access
Type Article
Web of Science ID WOS:000346083500016

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