Study of in vitro degradation of brushite cements scaffolds

Show simple item record Reno, Caroline de Oliveira [UNIFESP] Pereta, Nicholas C. [UNIFESP] Bertran, Celso A. Motisuke, Mariana [UNIFESP] Sousa, Eliandra de [UNIFESP] 2016-01-24T14:37:55Z 2016-01-24T14:37:55Z 2014-10-01
dc.identifier.citation Journal of Materials Science-materials in Medicine. Dordrecht: Springer, v. 25, n. 10, p. 2297-2303, 2014.
dc.identifier.issn 0957-4530
dc.description.abstract An interest path to fabricate supports for tissue engineering is to foam calcium phosphate cement's pastes leading to an increase on material's total porosity and interconnectivity which facilitates cells' adhesion, proliferation and differentiation. the aim of this work is to develop scaffolds of brushite cement and to evaluate its in vitro degradation rate. Macroporosity was obtained by foaming the liquid phase with different non-ionic surfactants (Tween 80 and Lutensol ON-110). the foam stability was achieved by adding chitosan. the scaffolds were immersed in Ringers(A (R)) solution during 7, 14, 21 and 28 days and samples' microstructure, weight loss, mechanical resistance and apparent porosity were evaluated. Both scaffolds presented interconnected macropores with sizes ranging from 100 to 360 A mu m and total porosities higher than 60 %. These properties could facilitate cell infiltration, bone growth and vascularization. the scaffolds obtained in this work should be considered as promising materials for application in bone tissue engineering. en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent 2297-2303
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof Journal of Materials Science-materials in Medicine
dc.rights Acesso restrito
dc.title Study of in vitro degradation of brushite cements scaffolds en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Universidade Estadual de Campinas (UNICAMP)
dc.description.affiliation Fed Univ São Paulo UNIFESP, Inst Sci & Technol, Bioceram Lab, BR-12231280 São Paulo, Brazil
dc.description.affiliation Univ Campinas UNICAMP, Inst Chem, Dept Phys Chem, Campinas, SP, Brazil
dc.description.affiliationUnifesp Fed Univ São Paulo UNIFESP, Inst Sci & Technol, Bioceram Lab, BR-12231280 São Paulo, Brazil
dc.description.sponsorshipID FAPESP: 2012/21198-0
dc.description.sponsorshipID FAPESP: 2010/00863-0
dc.description.sponsorshipID FAPESP: 2011/09240-9
dc.identifier.doi 10.1007/s10856-014-5269-2
dc.description.source Web of Science
dc.identifier.wos WOS:000342421300009


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