Conservative management of cervical pregnancy with embryonic heart activity by ultrasound-guided local injection: an eight case series

Conservative management of cervical pregnancy with embryonic heart activity by ultrasound-guided local injection: an eight case series

Author Elito Junior, Julio Autor UNIFESP Google Scholar
Musiello, Rubens Bermudes Autor UNIFESP Google Scholar
Araujo Junior, Edward Autor UNIFESP Google Scholar
Souza, Eduardo Autor UNIFESP Google Scholar
Fava, Jair Luiz Autor UNIFESP Google Scholar
Guerzet, Eduardo Almeida Autor UNIFESP Google Scholar
Camano, Luiz Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: To evaluate the efficacy of conservative management of cervical pregnancy with embryonic heart activity by ultrasound-guided local injection.Methods: Retrospective case series at University tertiary care Hospital. Eight patients diagnosed with cervical pregnancy with embryonic heart activity managed conservatively. the intervention was ultrasound-guided local injection of methotrexate (1 mg/kg) and potassium chloride (2 meq/mL). Measurements were occurrence of morbidity, necessity for further intervention, the initial titers of beta-hCG, interval of time in which the levels of beta-hCG became negative, period for regression of cervical pregnancy at ultrasound and future pregnancy.Results: All patients were treated successfully. the initial levels of beta-hCG ranged from 3013 to 71199 mUI/mL. One case evaluated with infection. There was no need for additional intervention in our series study. the interval of time for the levels of beta-hCG becomes negative range from 2 to 12 weeks. the period for the regression of the cervical pregnancy at ultrasound range from 3 to 14 weeks. in two cases intrauterine pregnancies occurred after the treatment.Conclusion: Conservative management of cervical pregnancy with embryonic heart activity by ultrasound-guided injection is an effective treatment avoiding the need of further intervention.
Keywords Cervical pregnancy
conservative management
methotrexate
potassium chloride injection
ultrasound
Language English
Date 2014-09-01
Published in Journal of Maternal-fetal & Neonatal Medicine. London: Informa Healthcare, v. 27, n. 13, p. 1378-1381, 2014.
ISSN 1476-7058 (Sherpa/Romeo, impact factor)
Publisher Informa Healthcare
Extent 1378-1381
Origin http://dx.doi.org/10.3109/14767058.2013.856413
Access rights Closed access
Type Article
Web of Science ID WOS:000340448800019
URI http://repositorio.unifesp.br/handle/11600/38205

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